Tenofovir diphosphate disodium
Based on 1 publication(s) in Google Scholar
Tenofovir diphosphate disodium is an antiretroviral agent. Tenofovir diphosphate disodium is an inhibitor of HIV reverse transcriptase DNA (Ki = 1.55 μM) and RNA (Ki = 0.022 μM). Tenofovir diphosphate disodium can be used for the research of AIDS.
For research use only. We do not sell to patients.
- Purity : 97.68%
- CAS No.: 2738719-07-6
- Formula: C9H14N5Na2O10P3
- Molecular Weight:491.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Tenofovir diphosphate disodium
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Biological Activity
Description
In Vitro
Tenofovir diphosphate disodium (1-2500 μM, 18-32 min) exhibits little inhibitory effect on eukaryotic DNA replication[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2738719-07-6
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Appearance Solid
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Molecular Weight 491.14
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Formula C9H14N5Na2O10P3
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Color White to off-white
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SMILES
C[C@@H](OC[P](O[P](O[P](O[Na])(O[Na])=O)(O)=O)(O)=O)CN1C2=NC=NC(N)=C2N=C1
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Synonyms
TFV-DP disodium
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Shipping
Shipping with dry ice.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Hepatol Commun
Capsid Allosteric Modulators Enhance the Innate Immune Response in Hepatitis B Virus-Infected Hepatocytes During Interferon Administration. [Abstract]2022 Feb;6(2):281-296. PMID: 34558845
Solvent & Solubility
In Vitro:
H2O : 100 mg/mL (203.61 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.0361 mL | 10.1804 mL | 20.3608 mL | 50.9020 mL |
| 5 mM | 0.4072 mL | 2.0361 mL | 4.0722 mL | 10.1804 mL | |
| 10 mM | 0.2036 mL | 1.0180 mL | 2.0361 mL | 5.0902 mL | |
| 15 mM | 0.1357 mL | 0.6787 mL | 1.3574 mL | 3.3935 mL | |
| 20 mM | 0.1018 mL | 0.5090 mL | 1.0180 mL | 2.5451 mL | |
| 25 mM | 0.0814 mL | 0.4072 mL | 0.8144 mL | 2.0361 mL | |
| 30 mM | 0.0679 mL | 0.3393 mL | 0.6787 mL | 1.6967 mL | |
| 40 mM | 0.0509 mL | 0.2545 mL | 0.5090 mL | 1.2725 mL | |
| 50 mM | 0.0407 mL | 0.2036 mL | 0.4072 mL | 1.0180 mL | |
| 60 mM | 0.0339 mL | 0.1697 mL | 0.3393 mL | 0.8484 mL | |
| 80 mM | 0.0255 mL | 0.1273 mL | 0.2545 mL | 0.6363 mL | |
| 100 mM | 0.0204 mL | 0.1018 mL | 0.2036 mL | 0.5090 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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