1. Anti-infection
  2. Reverse Transcriptase
  3. Tenofovir diphosphate

Tenofovir diphosphate (Synonyms: TFV-DP)

Cat. No.: HY-136548
Handling Instructions

Tenofovir diphosphate (TFV-DP) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT).

For research use only. We do not sell to patients.

Tenofovir diphosphate Chemical Structure

Tenofovir diphosphate Chemical Structure

CAS No. : 166403-66-3

Size Price Stock
5 mg USD 1500 Ask For Quote & Lead Time

* Please select Quantity before adding items.

Other In-stock Forms of Tenofovir diphosphate:

Other Forms of Tenofovir diphosphate:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Tenofovir diphosphate (TFV-DP) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT)[1].

IC50 & Target

DNA polymerases; HIV-1 reverse transcriptase[1]

In Vitro

Tenofovir diphosphate acts as an inhibitor of DNA pol. Tenofovir-diphosphate is a weak inhibitor of DNA polymerases (pol) α, δ, and ɛ, with values for the Ki for PMPApp (PMPAppKi) relative to the Km for dATP (dATPKm) of 10.2, 10.2, and 15.6, respectively[1].

Molecular Weight

447.17

Formula

C₉H₁₆N₅O₁₀P₃

CAS No.

166403-66-3

SMILES

C[[email protected]@H](OC[P](O[P](O[P](O)(O)=O)(O)=O)(O)=O)CN1C2=NC=NC(N)=C2N=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Tenofovir diphosphateTFV-DPReverse TranscriptaseDNApolymerasessubstrateHIVHIV-1reversetranscriptaseInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Tenofovir diphosphate
Cat. No.:
HY-136548
Quantity:
MCE Japan Authorized Agent: