1. Anti-infection
  2. Reverse Transcriptase
  3. Tenofovir diphosphate

Tenofovir diphosphate (Synonyms: TFV-DP)

Cat. No.: HY-136548
Handling Instructions

Tenofovir diphosphate (TFV-DP) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT).

For research use only. We do not sell to patients.

Tenofovir diphosphate Chemical Structure

Tenofovir diphosphate Chemical Structure

CAS No. : 166403-66-3

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Description

Tenofovir diphosphate (TFV-DP) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT)[1].

IC50 & Target

DNA polymerases; HIV-1 reverse transcriptase[1]

In Vitro

Tenofovir diphosphate acts as an inhibitor of DNA pol. Tenofovir-diphosphate is a weak inhibitor of DNA polymerases (pol) α, δ, and ɛ, with values for the Ki for PMPApp (PMPAppKi) relative to the Km for dATP (dATPKm) of 10.2, 10.2, and 15.6, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

447.17

Formula

C₉H₁₆N₅O₁₀P₃

CAS No.
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Tenofovir diphosphate
Cat. No.:
HY-136548
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