1. Anti-infection
  2. HIV
    Reverse Transcriptase

Rilpivirine (Synonyms: R278474; TMC278)

Cat. No.: HY-10574 Purity: 98.89%
Handling Instructions

Rilpivirine(R 278474, TMC 278) is a type of anti-HIV medicine called a non-nucleoside reverse transcriptase inhibitor (NNRTI).

For research use only. We do not sell to patients.

Rilpivirine Chemical Structure

Rilpivirine Chemical Structure

CAS No. : 500287-72-9

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 207 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
10 mg USD 188 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
50 mg USD 473 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Rilpivirine(R 278474, TMC 278) is a type of anti-HIV medicine called a non-nucleoside reverse transcriptase inhibitor (NNRTI). IC50 Value: Target: NNRTIs Rilpivirine(TMC278) is a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTI-resistant HIV-1. NNRTIs work by binding to and blocking HIV reverse transcriptase, an HIV enzyme. This prevents HIV from replicating and lowers the amount of HIV in the blood. Rilpivirine does not cure HIV/AIDS. It is not known if rilpivirine reduces the risk of passing HIV to other people.

Clinical Trial
References
Molecular Weight

366.42

Formula

C₂₂H₁₈N₆

CAS No.

500287-72-9

SMILES

CC1=CC(/C=C/C#N)=CC(C)=C1NC2=CC=NC(NC3=CC=C(C=C3)C#N)=N2

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Purity: 98.89%

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Product Name:
Rilpivirine
Cat. No.:
HY-10574
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