2. Metabolic Enzyme/Protease
  3. Angiotensin-converting Enzyme (ACE)
  4. Vicenin-1

Vicenin 1 is a C-glycosylflavone that has an inhibitory effect on angiotensin-converting enzyme (ACE)(IC50=52.50 μM).

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Vicenin-1

Vicenin-1 構造式

CAS 番号 : 35927-38-9

容量 価格（税別） 在庫状況 数量
5 mg $340 在庫あり
10 mg $540 在庫あり
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100 mg   お問い合わせ  

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Vicenin-1 関連抗体

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  • 純度とドキュメンテーション

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製品説明

Vicenin 1 is a C-glycosylflavone that has an inhibitory effect on angiotensin-converting enzyme (ACE)(IC50=52.50 μM)[1].

IC50 & Target

IC50: 52.50 μM (ACE)[1]
体外実験

The target-isolated C-glycosylflavone (Vicenin 1) is evaluated for inhibitory activities. Vicenin 1 embodies effective ACE inhibitory activities with an IC50 value of 52.50 μM. The tested compound 3 (Vicenin 1) shows activity via the generation of chelate complexes within the active center of ACE[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Vicenin-1 関連抗体
分子量

564.49

分子式

C26H28O14
CAS 番号
Appearance

Solid

Color

Off-white to yellow

SMILES

OC1=C([C@H]2[C@@H]([C@H]([C@H](O)CO2)O)O)C(O)=C(C(C=C(C3=CC=C(O)C=C3)O4)=O)C4=C1[C@@H]5O[C@@H]([C@@H](O)[C@H](O)[C@H]5O)CO
Structure Classification
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (177.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7715 mL 8.8576 mL 17.7151 mL
5 mM 0.3543 mL 1.7715 mL 3.5430 mL
10 mM 0.1772 mL 0.8858 mL 1.7715 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 98.60%

COA (256 KB) LCMS (109 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7715 mL 8.8576 mL 17.7151 mL 44.2878 mL
5 mM 0.3543 mL 1.7715 mL 3.5430 mL 8.8576 mL
10 mM 0.1772 mL 0.8858 mL 1.7715 mL 4.4288 mL
15 mM 0.1181 mL 0.5905 mL 1.1810 mL 2.9525 mL
20 mM 0.0886 mL 0.4429 mL 0.8858 mL 2.2144 mL
25 mM 0.0709 mL 0.3543 mL 0.7086 mL 1.7715 mL
30 mM 0.0591 mL 0.2953 mL 0.5905 mL 1.4763 mL
40 mM 0.0443 mL 0.2214 mL 0.4429 mL 1.1072 mL
50 mM 0.0354 mL 0.1772 mL 0.3543 mL 0.8858 mL
60 mM 0.0295 mL 0.1476 mL 0.2953 mL 0.7381 mL
80 mM 0.0221 mL 0.1107 mL 0.2214 mL 0.5536 mL
100 mM 0.0177 mL 0.0886 mL 0.1772 mL 0.4429 mL
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Vicenin-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vicenin-135927-38-9Vicenin1Vicenin 1Angiotensin-converting Enzyme (ACE)HypertensiondiureticcardiocerebrovascularInhibitorinhibitorinhibit

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製品名:
Vicenin-1
製品番号:
HY-125112
数量:
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