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Zedoalactone B is an anti-Babesial agent with an IC50 of 1.6 μg/mL against Babesia gibsoni. Zedoalactone B inhibits NO production with an IC50 of 23.8 μM.

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Zedoalactone B

Zedoalactone B Estructura química

No. CAS : 170384-81-3

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Descripciòn

Zedoalactone B is an anti-Babesial agent with an IC50 of 1.6 μg/mL against Babesia gibsoni. Zedoalactone B inhibits NO production with an IC50 of 23.8 μM[1][2].

Cellular Effect
Cell Line Type Value Description References
RAW264.7 IC50
1.3 μM
Compound: 22
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
[PMID: 23755850]
Peso molecular

280.32

Fòrmula

C15H20O5

No. CAS
SMILES

O[C@]([C@](O)(C=C1OC2=O)C)(CC[C@](O)3C)[C@]3([H])CC1=C2C

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Room temperature in continental US; may vary elsewhere.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
Zedoalactone B
Cat. No.:
HY-N10381
Cantidad:
MCE Japan Authorized Agent: