170384-81-3
170384-81-3
Chemical Structure
Zedoalactone B
- CAS No.: 170384-81-3
- Formula:C15H20O5
- Molecular Weight:280.32
IUPAC Name: (4aR,5S,7aR,8R)-5,7a,8-trihydroxy-3,5,8-trimethyl-4a,5,6,7,7a,8-hexahydroazuleno[6,5-b]furan-2(4H)-one
InChIKey: HPNXJLIPUVXDNH-FAAHXZRKSA-N
SMILES: O[C@]([C@](O)(C=C1OC2=O)C)(CC[C@](O)3C)[C@]3([H])CC1=C2C
Biological Activity: Zedoalactone B is an anti-Babesial agent with an IC50 of 1.6 μg/mL against Babesia gibsoni. Zedoalactone B inhibits NO production with an IC50 of 23.8 μM[1][2].
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Zedoalactone B | Zedoalactone B is an anti-Babesial agent with an IC50 of 1.6 μg/mL against Babesia gibsoni. Zedoalactone B inhibits NO production with an IC50 of 23.8 μM. | |||||||||||||||||||||
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References
- [1]. Kasahara K, et al. Anti-babesial compounds from Curcuma zedoaria. Planta Med. 2005 May;71(5):482-4. [Content Brief]
- [2]. Lou Y, et al. Guaiane-type sesquiterpenes from Curcuma wenyujin and their inhibitory effects on nitric oxide production. J Asian Nat Prod Res. 2009 Aug;11(8):737-47. [Content Brief]
Keywords
