2. Cell Cycle/DNA Damage Autophagy Apoptosis
  3. Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Autophagy Apoptosis
  4. ZPCK

ZPCK is an oral active proagent of gemcitabine that was designed for improved oral bioavailability.

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ZPCK

ZPCK Estructura química

No. CAS : 26049-94-5

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
100 mg En stock
250 mg En stock
500 mg   Obtener un presupuesto  
1 g   Obtener un presupuesto  

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ZPCK Related Antibodies

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RNASE L DNA Polymerases RNA Polymerases Helicases DNA Ligase

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Descripciòn

ZPCK is an oral active proagent of gemcitabine that was designed for improved oral bioavailability[1].

Peso molecular

331.79

Fòrmula

C18H18ClNO3
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

O=C(OCC1=CC=CC=C1)N[C@@H](CC2=CC=CC=C2)C(CCl)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 33 mg/mL (99.46 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0140 mL 15.0698 mL 30.1395 mL
5 mM 0.6028 mL 3.0140 mL 6.0279 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0140 mL 15.0698 mL 30.1395 mL 75.3489 mL
5 mM 0.6028 mL 3.0140 mL 6.0279 mL 15.0698 mL
10 mM 0.3014 mL 1.5070 mL 3.0140 mL 7.5349 mL
15 mM 0.2009 mL 1.0047 mL 2.0093 mL 5.0233 mL
20 mM 0.1507 mL 0.7535 mL 1.5070 mL 3.7674 mL
25 mM 0.1206 mL 0.6028 mL 1.2056 mL 3.0140 mL
30 mM 0.1005 mL 0.5023 mL 1.0047 mL 2.5116 mL
40 mM 0.0753 mL 0.3767 mL 0.7535 mL 1.8837 mL
50 mM 0.0603 mL 0.3014 mL 0.6028 mL 1.5070 mL
60 mM 0.0502 mL 0.2512 mL 0.5023 mL 1.2558 mL
80 mM 0.0377 mL 0.1884 mL 0.3767 mL 0.9419 mL
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ZPCK Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ZPCK26049-94-5SL-01SL01SL 01Nucleoside Antimetabolite/AnalogDNA/RNA SynthesisAutophagyApoptosisInhibitorinhibitorinhibit

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Nombre del producto:
ZPCK
Cat. No.:
HY-100709
Cantidad:
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