2. Membrane Transporter/Ion Channel Neuronal Signaling Metabolic Enzyme/Protease
  3. GABA Receptor Endogenous Metabolite
  4. γ-Aminobutyric acid-d6

γ-Aminobutyric acid-d6  (Synonyms: 4-Aminobutyric acid-d6)

製品番号: HY-N0067S 純度: 99.92%
COA 取扱説明書 Technical Support

γ-Aminobutyric acid-d6 is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors).

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γ-Aminobutyric acid-d<sub>6</sub>

γ-Aminobutyric acid-d6 構造式

CAS 番号 : 70607-85-1

容量 価格（税別） 在庫状況 数量
5 mg $80 在庫あり
10 mg $128 在庫あり
25 mg $256 お問い合わせ 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks
50 mg $390 在庫あり
100 mg $590 在庫あり
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500 mg   お問い合わせ  

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Based on 2 publication(s) in Google Scholar

Other Forms of γ-Aminobutyric acid-d6:

γ-Aminobutyric acid-d6 関連抗体

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製品説明

γ-Aminobutyric acid-d6 is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

体外実験

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

γ-Aminobutyric acid-d6 関連抗体
分子量

109.16

分子式

C4H3D6NO2
CAS 番号
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])N)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

H2O : 50 mg/mL (458.04 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 9.1609 mL 45.8043 mL 91.6086 mL
5 mM 1.8322 mL 9.1609 mL 18.3217 mL
10 mM 0.9161 mL 4.5804 mL 9.1609 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

純度: 99.92%

COA (250 KB) RP-HPLC (240 KB) MS (70 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 9.1609 mL 45.8043 mL 91.6086 mL 229.0216 mL
5 mM 1.8322 mL 9.1609 mL 18.3217 mL 45.8043 mL
10 mM 0.9161 mL 4.5804 mL 9.1609 mL 22.9022 mL
15 mM 0.6107 mL 3.0536 mL 6.1072 mL 15.2681 mL
20 mM 0.4580 mL 2.2902 mL 4.5804 mL 11.4511 mL
25 mM 0.3664 mL 1.8322 mL 3.6643 mL 9.1609 mL
30 mM 0.3054 mL 1.5268 mL 3.0536 mL 7.6341 mL
40 mM 0.2290 mL 1.1451 mL 2.2902 mL 5.7255 mL
50 mM 0.1832 mL 0.9161 mL 1.8322 mL 4.5804 mL
60 mM 0.1527 mL 0.7634 mL 1.5268 mL 3.8170 mL
80 mM 0.1145 mL 0.5726 mL 1.1451 mL 2.8628 mL
100 mM 0.0916 mL 0.4580 mL 0.9161 mL 2.2902 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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γ-Aminobutyric acid-d6 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

γ-Aminobutyric acid-d670607-85-14-Aminobutyric acid-d6GABA ReceptorEndogenous MetaboliteGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorInhibitorinhibitorinhibit

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