56-12-2
56-12-2
Chemical Structure
γ-Aminobutyric acid
Synonym(s): 4-Aminobutyric acid
- CAS No.: 56-12-2
- Formula:C4H9NO2
- Molecular Weight:103.12
IUPAC Name: 4-aminobutanoic acid
InChIKey: BTCSSZJGUNDROE-UHFFFAOYSA-N
SMILES: O=C(O)CCCN
Biological Activity: γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors. γ-Aminobutyric acid shows calming effect by blocking specific signals of central nervous system[1][2].
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γ-Aminobutyric acid | 99.71% | γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors. γ-Aminobutyric acid shows calming effect by blocking specific signals of central nervous system. | ||||||||||||||||||||
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γ-Aminobutyric acid (Standard) | 99.93% | γ-Aminobutyric acid (Standard) is the analytical standard of γ-Aminobutyric acid. This product is intended for research and analytical applications. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors. γ-Aminobutyric acid shows calming effect by blocking specific signals of central nervous system. | ||||||||||||||||||||
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γ-Aminobutyric acid-d2 | 99.95% | γ-Aminobutyric acid-d2 is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors). | ||||||||||||||||||||
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γ-Aminobutyric acid-4,4-d2 | γ-Aminobutyric acid-4,4-d2 is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors). | |||||||||||||||||||||
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γ-Aminobutyric acid-13C4 | 99.95% | γ-Aminobutyric acid-13C4 is the 13C-labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors). | ||||||||||||||||||||
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γ-Aminobutyric acid-15N | 98.04% | γ-Aminobutyric acid-15N (4-Aminobutyric acid-15N) is the 15N-labeled γ-Aminobutyric acid (HY-N0067). γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors. γ-Aminobutyric acid shows calming effect by blocking specific signals of central nervous system. | ||||||||||||||||||||
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γ-Aminobutyric acid-d6 | 99.92% | γ-Aminobutyric acid-d6 is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors). | ||||||||||||||||||||
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Aminoadipic acid-d3 | 98.95% | Aminoadipic acid-d3 is the deuterium labeled Aminoadipic acid. Aminoadipic acid is an intermediate in the metabolism of lysine and saccharopine. | ||||||||||||||||||||
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Octanoic acid-d2 | Octanoic acid-d2 is the deuterium labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes. | |||||||||||||||||||||
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6-Aminocaproic acid hydrochloride | 6-Aminocaproic acid hydrochloride, a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders. | |||||||||||||||||||||
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6-Aminocaproic acid (Standard) | ≥98% | 6-Aminocaproic acid (Standard) is the analytical standard of 6-Aminocaproic acid. This product is intended for research and analytical applications. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders. | ||||||||||||||||||||
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6-Aminocaproic acid-d10 | 6-Aminocaproic acid-d10 is the deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders. | |||||||||||||||||||||
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β-Alanine (Standard) | 99.93% | β-Alanine (Standard) is the analytical standard of β-Alanine. This product is intended for research and analytical applications. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer. | ||||||||||||||||||||
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β-Alanine-13C3,15N | 99.99% | β-Alanine-13C3,15N is the 13C- and 15N-labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer. | ||||||||||||||||||||
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β-Alanine-15N | 98.0% | β-Alanine-15N is the 15N-labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer. | ||||||||||||||||||||
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β-Alanine-d4 | 99.90% | β-Alanine-d4 is the deuterium labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer. | ||||||||||||||||||||
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β-Alanine-13C | β-Alanine-13C (2-Carboxyethylamine-13C) is 13C labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer. | |||||||||||||||||||||
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5-Aminolevulinic acid-d2 hydrochloride | 91.20% | 5-Aminolevulinic acid-d2 (hydrochloride) is deuterium labeled 5-Aminolevulinic acid (hydrochloride). | ||||||||||||||||||||
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Nonanoic acid-d2 | 98.0% | Nonanoic acid (Pelargonic acid)-d2 is the deuterium labeled Nonanoic acid (HY-N7057). Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2. | ||||||||||||||||||||
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7-Aminoheptanoic acid | 97.0% | 7-Aminoheptanoic acid is a PROTAC linker. 7-Aminoheptanoic acid can be used to synthesize PROTAC molecules (e.g. HL-8 (HY-143275)). | ||||||||||||||||||||
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L-2-Aminobutyric acid-d6 | 99.92% | L-2-Aminobutyric acid-d6 is the deuterium labeled L-2-Aminobutyric acid. L-2-Aminobutyric acid is a non-proteinogenic amino acid that exists in human tissues and body fluids. L-2-Aminobutyric acid is formed by the transamination of oxobutyric acid. L-2-Aminobutyric acid can serve as a precursor for anticonvulsant and anti-tuberculosis agents and is a key intermediate in the chemical and pharmaceutical industries. | ||||||||||||||||||||
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H-DL-Abu-OH-d6 | 99.98% | H-DL-Abu-OH-d6 is the deuterium labeled H-DL-Abu-OH. | ||||||||||||||||||||
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4-Bromobutanoic acid-d6 | 4-Bromobutanoic acid-d6 (4-Bromobutyric acid-d6) is the deuterium labeled 4-Bromobutanoic acid. | |||||||||||||||||||||
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2-Bromobutanoic acid-d6 | 2-Bromobutanoic acid-d6 is the deuterium labeled 2-Bromobutanoic acid. | |||||||||||||||||||||
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5-Aminovaleric acid | 99.90% | 5-Aminovaleric acid is believed to act as a methylene homologue of gamma-aminobutyric acid (GABA) and functions as a weak GABA agonist. | ||||||||||||||||||||
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L-Ornithine-d7 hydrochloride | 99.62% | L-Ornithine-d7 hydrochloride is the d7-labeled L-Ornithine hydrochloride (HY-W017018). L-Ornithine hydrochloride is an orally active CaSR and p38 activator. L-Ornithine hydrochloride inhibits ROS and supports urea cycle function. L-Ornithine hydrochloride can be used to study kidney diseases involving proximal tubular cell damage caused by oxidative stress or crystallopathy, as well as research related to anxiety disorders. | ||||||||||||||||||||
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(R)-3-Amino-2-methylpropanoic acid-d3 | (R)-3-Amino-2-methylpropanoic acid-d3 is the deuterium labeled (R)-3-Amino-2-methylpropanoic acid. | |||||||||||||||||||||
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5-Aminopentanoic acid hydrochloride | 5-Aminopentanoic acid hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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2-Chlorobutanoic acid-d6 | 98.4% | 2-Chlorobutanoic acid-d6 is the deuterium labeled 2-Chlorobutanoic acid. | ||||||||||||||||||||
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D(-)-2-Aminobutyric acid-d6 | D(-)-2-Aminobutyric acid-d6 is the deuterium labeled D(-)-2-Aminobutyric acid. D(-)-2-Aminobutyric acid is a substrate of D-amino acid oxidase. | |||||||||||||||||||||
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References
- [1]. Chen S, et al. Effects of dietary gamma-aminobutyric acid supplementation on the intestinal functions in weaning piglets. Food Funct. 2019 Jan 2. [Content Brief]
- [2]. Okada R, et al. Gamma-aminobutyric acid (GABA)-mediated neural connections in the Drosophila antennal lobe. J Comp Neurol. 2009 May 1;514(1):74-91. [Content Brief]
