1. Anti-infection
  2. Parasite
  3. 2,3-Diphosphoglyceric acid

2,3-Diphosphoglyceric acid (2,3-DPG) is an intermediate of the glycolytic pathway. 2,3-Diphosphoglyceric acid stabilizes the deoxygenated form of hemoglobin by allosteric binding and facilitates oxygen release at tissue sites. 2, 3-diphosphoglyceric acid has antiparasitic activity. 2,3-Diphosphoglyceric acid can be used in the study of Alzheimer's disease (AD).

The free form of the compound is prone to instability, it is advisable to consider the stable salt form (2,3-Diphosphoglyceric acid pentasodium) that retains the same biological activity.

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2,3-Diphosphoglyceric acid

2,3-Diphosphoglyceric acid Estructura química

No. CAS : 138-81-8

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Descripciòn

2,3-Diphosphoglyceric acid (2,3-DPG) is an intermediate of the glycolytic pathway. 2,3-Diphosphoglyceric acid stabilizes the deoxygenated form of hemoglobin by allosteric binding and facilitates oxygen release at tissue sites. 2, 3-diphosphoglyceric acid has antiparasitic activity. 2,3-Diphosphoglyceric acid can be used in the study of Alzheimer's disease (AD)[1][2][3][4].

Cellular Effect
Cell Line Type Value Description References
T-cell EC50
1580 3
Compound: 2,3-diphosphoglycerate
Effective concentration to activate gammadelta T cells
Effective concentration to activate gammadelta T cells
[PMID: 12383012]
T-cell EC50
1580 3
Compound: 2,3-diphosphoglycerate
Effective concentration to activate gammadelta T cells
Effective concentration to activate gammadelta T cells
[PMID: 12383012]
In Vitro

2, 3-diphosphoglyceric acid (8 mM, 48 h) inhibits the development of Plasmodium falciparum[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

266.04

Fòrmula

C3H8O10P2

No. CAS
SMILES

O=C(O)C(OP(O)(O)=O)COP(O)(O)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
2,3-Diphosphoglyceric acid
Cat. No.:
HY-113050
Cantidad:
MCE Japan Authorized Agent: