1. Protein Tyrosine Kinase/RTK
  2. Src
    Bcr-Abl

Bosutinib (Synonyms: SKI-606)

Cat. No.: HY-10158 Purity: 99.83%
Handling Instructions

Bosutinib is a dual Src/Abl inhibitor with IC50s of 1.2 nM and 1 nM, respectively.

For research use only. We do not sell to patients.

Bosutinib Chemical Structure

Bosutinib Chemical Structure

CAS No. : 380843-75-4

Size Stock
10 mM * 1 mL in DMSO Get quote
10 mg USD 60 Get quote
50 mg USD 120 Get quote
100 mg USD 180 Get quote
200 mg USD 216 Get quote

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Description

Bosutinib is a dual Src/Abl inhibitor with IC50s of 1.2 nM and 1 nM, respectively.

Solvent & Solubility
In Vitro: 

DMSO : ≥ 46 mg/mL (86.72 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8852 mL 9.4260 mL 18.8519 mL
5 mM 0.3770 mL 1.8852 mL 3.7704 mL
10 mM 0.1885 mL 0.9426 mL 1.8852 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

530.45

Formula

C₂₆H₂₉Cl₂N₅O₃

CAS No.

380843-75-4

SMILES

CN1CCN(CC1)CCCOC2=C(C=C3C(NC4=CC(OC)=C(C=C4Cl)Cl)=C(C=NC3=C2)C#N)OC

Storage

4°C, protect from light

Shipping

Room temperature in continental US; may vary elsewhere

Purity: 99.83%

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Bosutinib
Cat. No.:
HY-10158
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Bosutinib

Cat. No.: HY-10158