Galactose 1-phosphate

製品番号: HY-113143: Data Sheet 取扱説明書
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Galactose 1-phosphate acts as a competitive substrate inhibitor of galactose-1-phosphate uridylyltransferase (GALT). Galactose 1-phosphate is a competitive inhibitor of Phosphoglucomutase, yet the rate at which this enzyme converts Galactose 1-phosphate to Galactose-6-phosphate is 400 times slower than the rate of converting Glucose-1-phosphate. Galactose 1-phosphate can be used in studies related to Saccharomyces cerevisiae infection and type I galactosemia.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Galactose 1-phosphate Potassium salt) usually boasts enhanced water solubility and stability.

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Galactose 1-phosphate 構造式

CAS 番号 : 2255-14-3

容量	価格（税別）	在庫状況
5 mg	$100	見積もりとリードタイムを求めるのご確認
10 mg	$170	見積もりとリードタイムを求めるのご確認
25 mg	$340	見積もりとリードタイムを求めるのご確認
50 mg	$550	見積もりとリードタイムを求めるのご確認

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

Other 在庫あり Forms of Galactose 1-phosphate:

Galactose 1-phosphate Potassium salt

Other Forms of Galactose 1-phosphate:

Galactose 1-phosphate Potassium salt 在庫あり

Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Human Endogenous Metabolite Microbial Metabolite

生物活性
純度とドキュメンテーション
参考文献
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製品説明

IC₅₀ & Target

Human Endogenous Metabolite

体外実験

Galactose 1-phosphate acts as a competitive substrate inhibitor of Escherichia coli galactose-1-phosphate uridylyltransferase (GALT), which can displace UMP from the covalently bound UMP-GALT intermediate to form UDP-galactose^[1].
Galactose 1-phosphate acts as a competitive inhibitor of Phosphoglucomutase, yet the reaction rate at which this enzyme converts Galactose 1-phosphate to galactose-6-phosphate is 400 times slower than that of glucose-1-phosphate conversion^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

260.14

分子式

C₆H₁₃O₉P

CAS 番号

2255-14-3

SMILES

O=P(O)(O)O[C@H]1O[C@@H]([C@H](O)[C@H](O)[C@H]1O)CO

Structure Classification

Saccharides

Initial Source

Microorganisms

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. McCorvie TJ, et al. The structural and molecular biology of type I galactosemia: Enzymology of galactose 1-phosphate uridylyltransferase. IUBMB Life. 2011;63(9):694-700. [Content Brief]

[2]. de Jongh WA, et al. The roles of galactitol, galactose-1-phosphate, and phosphoglucomutase in galactose-induced toxicity in Saccharomyces cerevisiae. Biotechnol Bioeng. 2008;101(2):317-326.