1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Galactose 1-phosphate

Galactose 1-phosphate acts as a competitive substrate inhibitor of galactose-1-phosphate uridylyltransferase (GALT). Galactose 1-phosphate is a competitive inhibitor of Phosphoglucomutase, yet the rate at which this enzyme converts Galactose 1-phosphate to Galactose-6-phosphate is 400 times slower than the rate of converting Glucose-1-phosphate. Galactose 1-phosphate can be used in studies related to Saccharomyces cerevisiae infection and type I galactosemia.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Galactose 1-phosphate Potassium salt) usually boasts enhanced water solubility and stability.

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Galactose 1-phosphate

Galactose 1-phosphate Estructura química

No. CAS : 2255-14-3

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Descripciòn

Galactose 1-phosphate acts as a competitive substrate inhibitor of galactose-1-phosphate uridylyltransferase (GALT). Galactose 1-phosphate is a competitive inhibitor of Phosphoglucomutase, yet the rate at which this enzyme converts Galactose 1-phosphate to Galactose-6-phosphate is 400 times slower than the rate of converting Glucose-1-phosphate. Galactose 1-phosphate can be used in studies related to Saccharomyces cerevisiae infection and type I galactosemia[1][2].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Galactose 1-phosphate acts as a competitive substrate inhibitor of Escherichia coli galactose-1-phosphate uridylyltransferase (GALT), which can displace UMP from the covalently bound UMP-GALT intermediate to form UDP-galactose[1].
Galactose 1-phosphate acts as a competitive inhibitor of Phosphoglucomutase, yet the reaction rate at which this enzyme converts Galactose 1-phosphate to galactose-6-phosphate is 400 times slower than that of glucose-1-phosphate conversion[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

260.14

Fòrmula

C6H13O9P

No. CAS
SMILES

O=P(O)(O)O[C@H]1O[C@@H]([C@H](O)[C@H](O)[C@H]1O)CO

Structure Classification
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Inquiry Information

Nombre del producto:
Galactose 1-phosphate
Cat. No.:
HY-113143
Cantidad:
MCE Japan Authorized Agent: