2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-108053
    CDRI-97/78 372960-05-9 98%
    CDRI-97/78 is an antimalarial agent. CDRI-97/78 has phototoxicity and can induce cell apoptosis and G2/M phase arrest. CDRI-97/78 can be used for the research of infection.
    CDRI-97/78
  • HY-108080
    BAL-0019764 404824-79-9 98%
    BAL-0019764 is an iron carrier monocyclic β-lactam with broad-spectrum β-lactase inhibition ability. BAL-0019764 has inhibitory activity against various Gram negative bacteria. BAL-0019764 is commonly used in the study of bacterial infections.
    BAL-0019764
  • HY-108191
    Paldimycin A 101411-70-5 98%
    Paldimycin A (Antibiotic 273a1α) is an antibiotic derived from Streptomyces paulus, primarily targeting Gram-positive bacteria. Paldimycin A exerts its antibacterial effects by interfering with bacterial protein synthesis and cell membrane function.
    Paldimycin A
  • HY-108255
    HIV-1 inhibitor-60 1443461-21-9 98%
    HIV-1 inhibitor-60 (compound 45) is an HIV inhibitor with the potential for the research of infection diseases.
    HIV-1 inhibitor-60
  • HY-10852A
    Arterolane maleate 959520-73-1 98%
    Arterolane (OZ 277) (maleate) is an orally active antimalarial. Arterolane exhibits potent activity against erythrocytic stages of P. falciparum and Plasmodium vivax. Arterolane (maleate) is promising for research of falciparum malaria.
    Arterolane maleate
  • HY-10852R
    Arterolane (Standard) 664338-39-0
    Arterolane (Standard) is the analytical standard of Arterolane. This product is intended for research and analytical applications. Arterolane is an antimalarial agent, with IC50 of both 1.1 nM against P. falciparum Ro73 and W2, respectively.
    Arterolane (Standard)
  • HY-10870R
    RO-9187 (Standard) 876708-03-1
    RO-9187 (Standard) is the analytical standard of RO-9187 (HY-10870). This product is intended for research and analytical applications. RO-9187 is a potent inhibitor of HCV virus replication with an IC50 of 171 nM. RO-9187 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    RO-9187 (Standard)
  • HY-108930
    HI-207 244268-79-9 98%
    HI-207 is a non-nucleoside reverse transcriptase inhibitor. HI-207 has anti-HIV activity (PBMC/p24 inhibition assay: IC50 = 0.27 μM). HI-207 can be used for HIV infection research.
    HI-207
  • HY-108954
    A-30912A nucleus hydrochloride 1029890-89-8 99.84%
    A-30912A nucleus hydrochloride is the product of Echinocandin B (ECB) deacylase-catalyzed antifungal agent A-30912A (HY-125723).
    A-30912A nucleus hydrochloride
  • HY-108988
    Albicidin 1622253-00-2 98%
    Albicidin is a peptide antibiotic with phytotoxic activity. Albicidin potently inhibits bacterial and plant DNA gyrase at nanomolar concentrations, blocks DNA replication, and exhibits excellent antibacterial efficacy against multidrug-resistant bacteria. Albicidin possesses bactericidal activity against Gram-positive and Gram-negative microorganisms, and acts as a virulence factor for the systemic plant infection by Xanthomonas albilineans. Albicidin can be used in studies related to bacterial infections and sugarcane leaf blight.
    Albicidin
  • HY-108989
    FMDP 96920-07-9 98%
    FMDP is an inhibitor of GlcN-6-P Synthase with an anti-candidal activity. FMDP can be covalently attached to a polyethylene glycol as a nanoparticle shows strong anticancer activity.
    FMDP
  • HY-109072
    Riamilovir 123606-06-4 98%
    Riamilovir is an antiviral drug whose activity is primarily directed against RNA viruses. Riamilovir acts directly on the virus's RNA-dependent RNA polymerase, thereby preventing the virus from replicating. This mechanism allows Riamilovir to effectively reduce the amount of virus, accelerate the relief of symptoms, and help reduce the severity of the disease. Riamilovir can be used in the study of acute respiratory viral infections caused by new variants of SARS-CoV-2.
    Riamilovir
  • HY-109125
    SPK-843 143483-67-4 98%
    SPK-843 is an antifungal agent. SPK-843 shows inhibitory activity against A. fumigatus MF-13, A. flavus TIMM 0057, and A. niger TIMM 2814 with MICs of 0.5 μg/mL, 0.25 μg/mL, and 0.0625 μg/mL, respectively. SPK-843 exhibits dose-dependent efficacy in murine models of pulmonary aspergillosis. SPK-843 can be used for the research of related fungal infections.
    SPK-843
  • HY-10964R
    Vadimezan (Standard) 117570-53-3 98%
    Vadimezan (Standard) (DMXAA (Standard)) is the analytical standard of Vadimezan (HY-10964). This product is intended for research and analytical applications. Vadimezan (DMXAA; ASA-404), the tumor vascular disrupting agent (tumor-VDA), is a murine agonist of the stimulator of interferon genes (STING) and also a potent inducer of type I IFNs and other cytokines. Vadimezan is unable to activate human STING. Vadimezan has anti-influenza virus H1N1-PR8 activities.
    Vadimezan (Standard)
  • HY-109796
    NIK250 1000817-20-8 98%
    NIK250 is a potent multiple drug resistance (MDR) reversal agent that inhibits P-glycoprotein.
    NIK250
  • HY-10980R
    Tavaborole (Standard) 174671-46-6 98%
    Tavaborole (Standard) is the analytical standard of Tavaborole. This product is intended for research and analytical applications. Tavaborole (AN-2690) is an antifungal agent with activity against Trichophyton species, in a topical solution formulation for the potential treatment of onychomycosis.
    Tavaborole (Standard)
  • HY-110061
    (2R,4R,6S)-Tubacin 1350555-93-9 98%
    (2R,4R,6S)-Tubacin is the 2R,4R,6S enantiomer of Tubacin (HY-13428). Tubacin is a potent and selective inhibitor of HDAC6, with an IC50 value of 4 nM and approximately 350-fold selectivity over HDAC1. Tubacin also inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2).
    (2R,4R,6S)-Tubacin
  • HY-110093
    UNC0638 hydrate 1255517-77-1 98%
    UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 of 15 nM and 19 nM, respectively. UNC0638 hydrate inhibits TNBC cell invasion and migration in vitro. UNC0638 hydrate is also an inhibitor of EHMT1/2 and induces fetal hemoglobin (HbF) expression in human erythroid progenitor cell culture. In addition, UNC0638 hydrate has anti-FMDV (foot-and-mouth disease virus) and anti-VSV (vesicular stomatitis virus) activities, with excellent potency and selectivity against multiple epigenetic and non-epigenetic targets.
    UNC0638 hydrate
  • HY-111019
    SCH 34343 95415-91-1 98%
    SCH 34343 is a penem antibiotic. SCH 34343 is highly active against Streptococcus pneumoniae (MIC50 ≤ 0.015 mg/L), viridans streptococci (MIC50 = 0.06 mg/L), streptococci of groups A (MIC50 = 0.03 mg/L), B (MIC50 = 0.06 mg/L), C and G (MIC50 = 0.03 mg/L), and Str. bovis. SCH 34343 can be used for antibacterial research.
    SCH 34343
  • HY-111026
    PPQ-581 950381-32-5 98%
    PPQ-581 is an anti-influenza agent with an EC50 of 1 μM for preventing virus-induced cytopathic effects. PPQ-581 inhibits viral protein synthesis. PPQ-581 blocks the RNP nuclear export and cytoplasmic RNP aggregation.
    PPQ-581
Cat. No. Product Name / Synonyms Application Reactivity