2. Inflammation/Immunology

Inflammation/Immunology (炎症/免疫)

Inflammation/Immunology

関連製品

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

製品番号 製品名 CAS 番号 純度 構造式
  • HY-N2399
    Diffractaic acid 436-32-8 99.58%
    Diffractaic acid, a major constituent of U. longissimi, acts as an effective proapoptotic agent in various disorders research. Diffractaic acid is the analgesic and antipyretic component of Usnea diffracta.
    Diffractaic acid
  • HY-N2896
    Arjunolic acid

    Arjunolic acid

    		465-00-9 98.83%
    Arjunolic acid is an orally active, multifunctional bioactive compound. Arjunolic acid exhibits free radical scavenging activity, as well as fungal and bacterial activities. Arjunolic acid induces apoptosis (Apoptosis) in various cancer cells. Arjunolic acid protects hepatocytes against induced oxidative stress and apoptosis by reducing reactive oxygen species and inhibiting NF-κB activation. Arjunolic acid regulates pancreatic dysfunction in type 2 diabetic rats by blocking the activation of the TLR-4/MyD88 and canonical Wnt pathways. Arjunolic acid inhibits neuroinflammation and ameliorates depressive behaviors via the SIRT1/AMPK/Notch1 signaling pathway in microglia. Arjunolic acid improves Crohn's disease-like colitis by restoring gut microbiota composition and inhibiting TLR4 signaling. Arjunolic acid suppresses osteosarcoma progression by inhibiting Wnt3a-mediated M2 polarization of macrophages. Arjunolic acid ameliorates diabetic retinopathy via the autophagy pathway regulated by AMPK/mTOR/HO-1. Arjunolic acid is applicable to research related to type 2 diabetes, organ toxicity, depression, Crohn's disease, osteosarcoma, diabetic retinopathy, and testicular dysfunction.
    Arjunolic acid
  • HY-N3500
    Ganoderic acid D2 97653-94-6 99.69%
    Ganoderic acid D2 (compound 27) is a triterpenoid isolated from Ganoderma lucidum. Ganoderic acid D2 has anticancer, anti-inflammatory and antioxidative activity.
    Ganoderic acid D2
  • HY-N3963
    Gomisin M2 82425-45-4 99.75%
    Gomisin M2 ((+)-Gomisin M2) is a lignan isolated from the fruits of Schisandra rubriflora with anti-HIV activity (EC50 of 2.4 μM). Gomisin M2 exhibits anti-cancer and anti-allergic activities and has the potential for Alzheimer’s disease research.
    Gomisin M2
  • HY-N4030
    Humantenmine 82354-38-9 99.65%
    Humantenmine, a newalkaloid isolated from Gelsemium elegan Banth in China, has the potential for pain and rheumatic arthritis treatment.
    Humantenmine
  • HY-N4231
    Lucyoside B 91174-19-5 99.21%
    Lucyoside B inhibits the production of inflammatory mediators via both NF-κB and activator protein-1 pathways in activated macrophages.
    Lucyoside B
  • HY-N4290
    3-Epioleanolic acid 25499-90-5 99.89%
    3-Epioleanolic acid is an active component of Verbena officinalis Linn, with anti-inflammatory activity.
    3-Epioleanolic acid
  • HY-N4312
    Bryodulcosigenin 88930-16-9 99.21%
    Bryodulcosigenin is an extract of the roots of Bryoniadioica with anti-inflammatory effect.
    Bryodulcosigenin
  • HY-N4327
    Eurycomalactone 23062-24-0 99.74%
    Eurycomalactone is an active quassinoid could be isolated from Eurycoma longifolia Jack. Eurycomalactone is a potent NF-κB inhibitor with an IC50 value of 0.5 μM. Eurycomalactone inhibits protein synthesis and depletes cyclin D1. Eurycomalactone enhances radiosensitivity through arrest cell cycle at G2/M phase and delayed DNA double-strand break repair. Eurycomalactone inhibits the activation of AKT/NF-κB signaling, induces apoptosis and enhances chemosensitivity to Cisplatin (HY-17394).
    Eurycomalactone
  • HY-N6039
    Gentianine 439-89-4 98.0%
    Gentianine, an active metabolite of Swertiamarin, has anti-diabetic effect and anti-inflammatory property.
    Gentianine
  • HY-N6577
    Astragaloside VI 84687-45-6 99.95%
    Astragaloside VI could activate EGFR/ERK signalling pathway to improve wound healing.
    Astragaloside VI
  • HY-N6642
    Ankaflavin 50980-32-0 98.22%
    Ankaflavin, isolated from Monascus-Fermented red rice, is an orally active PPARγ agonist. Ankaflavin exhibits selective cytotoxic effect and induces cell death through apoptosis on cancer cells. Ankaflavin has anti-inflammatory, anti-cancer, antiatherosclerotic, and hypolipidemic effects.
    Ankaflavin
  • HY-N6643
    Rubropunctamine 514-66-9
    Rubropunctamine is a redMonascus pigment. Not only Rubropunctamine exerts antibiotic action against bacteria but also against some yeast and filamentous fungi strains. Rubropunctamine has potential embryotoxicity and teratogenicity.
    Rubropunctamine
  • HY-N6908
    Continentalic acid 19889-23-7 99.72%
    Continentalic acid is a diterpenoid organic acid. Continentalic acid exhibits multiple activities including anti-inflammatory, antioxidant, neuroprotective, antibacterial and antitumor effects. Continentalic acid alleviates oxidative stress, reduces pro-inflammatory cytokine production, inhibits MAPK phosphorylation and neutrophil infiltration, and induces growth inhibition and apoptosis of cancer cells. Continentalic acid can be used in research related to traumatic brain injury, cancer, inflammation and infections.
    Continentalic acid
  • HY-N7031
    (±)​-​Vasicine 6159-56-4 99.46%
    (±)-Vasicine is the racemate of Vasicine. Vasicine (Peganine) significantly inhibits H+-K+-ATPase activity in vitro with an IC50 of 73.47 μg/mL. Anti-ulcer activity. Vasicine shows significant anti-secretory, antioxidant and cytoprotective effect.
    (±)​-​Vasicine
  • HY-N7903
    Complanatoside B 142473-99-2 99.74%
    Complanatoside B is a P. chinense Fisch flavonoid with potential anti-inflammatory effects.
    Complanatoside B
  • HY-N7905
    Myricetin 3'-glucoside 520-14-9 99.98%
    Myricetin 3'-glucoside is a glycoside derivative of quercetin. Myricetin 3'-glucoside significantly prevents ethanol-induced hepatotoxicity by reducing hepatic transaminase activity and inflammatory response in HepG2 cells. Myricetin 3'-glucoside has a certain protective effect on alcohol-induced liver injury.
    Myricetin 3'-glucoside
  • HY-N8126
    Emodin 6-O-β-D-glucoside 34298-85-6 98.00%
    Emodin-6-O-β-D-glucoside (Glucoemodin) is an active compound from Reynoutria japonica. Emodin-6-O-β-D-glucoside shows potent anti-inflammatory and barrier protective effects. Emodin-6-O-β-D-glucoside can be used for the research of diabetic complications and atherosclerosis.
    Emodin 6-O-β-D-glucoside
  • HY-N8184
    4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone 151752-08-8 99.64%
    4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone exhibits COX-1 and COX-2 inhibitory activity.
    4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone
  • HY-N8251
    Cyclocurcumin 153127-42-5 99.48%
    Cyclocurcumin is a potent p38α inhibitor. Cyclocurcumin shows antirheumatic, antivasoconstrictive and antioxidant activities.
    Cyclocurcumin
製品番号 製品名 / Synonyms Application Reactivity