4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone
Based on 1 Customer Validation
4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone exhibits COX-1 and COX-2 inhibitory activity.
For research use only. We do not sell to patients.
- Purity: 99.64%
- CAS No.: 151752-08-8
- Formula: C17H18O5
- Molecular Weight:302.32
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
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Biological Activity
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COX-1 |
COX-2 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
42.9 μM
Compound: 24
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Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
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[PMID: 19689125] |
| B16-BL6 | IC50 |
84.4 μM
Compound: 24
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Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
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[PMID: 19689125] |
| HeLa | IC50 |
49 μM
Compound: 24
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Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
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[PMID: 19689125] |
| HT-1080 | IC50 |
67.2 μM
Compound: 24
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Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
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[PMID: 19689125] |
Chemical Information
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CAS No. 151752-08-8
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Appearance Solid
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Molecular Weight 302.32
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Formula C17H18O5
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Color White to off-white
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SMILES
O=C(C1=CC=C(O)C=C1)CCC2=C(OC)C=C(O)C=C2OC
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 25 mg/mL (82.69 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3078 mL | 16.5388 mL | 33.0775 mL | 82.6938 mL |
| 5 mM | 0.6616 mL | 3.3078 mL | 6.6155 mL | 16.5388 mL | |
| 10 mM | 0.3308 mL | 1.6539 mL | 3.3078 mL | 8.2694 mL | |
| 15 mM | 0.2205 mL | 1.1026 mL | 2.2052 mL | 5.5129 mL | |
| 20 mM | 0.1654 mL | 0.8269 mL | 1.6539 mL | 4.1347 mL | |
| 25 mM | 0.1323 mL | 0.6616 mL | 1.3231 mL | 3.3078 mL | |
| 30 mM | 0.1103 mL | 0.5513 mL | 1.1026 mL | 2.7565 mL | |
| 40 mM | 0.0827 mL | 0.4135 mL | 0.8269 mL | 2.0673 mL | |
| 50 mM | 0.0662 mL | 0.3308 mL | 0.6616 mL | 1.6539 mL | |
| 60 mM | 0.0551 mL | 0.2756 mL | 0.5513 mL | 1.3782 mL | |
| 80 mM | 0.0413 mL | 0.2067 mL | 0.4135 mL | 1.0337 mL |
4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone Related Classifications
HY-N8184 Related Classifications
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