2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-121362R
    Evernic Acid (Standard)
    		Inhibitor
    Propazine (Standard) is the analytical standard of Propazine. This product is intended for research and analytical applications. Propazine is a triazine herbicide that effectively manages broad-leaved weeds and annual grasses in sweet sorghum cultivation.
    Evernic Acid (Standard)
  • HY-N6687C
    Calcimycin hemicalcium hemimagnesium
    		Inhibitor
    Calcimycin (A-23187) hemicalcium hemimagnesium is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemicalcium hemimagnesium induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemicalcium hemimagnesium inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin hemicalcium hemimagnesium also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin hemicalcium hemimagnesium induces apoptosis and autophagy.
    Calcimycin hemicalcium hemimagnesium
  • HY-N18710
    Nepeta cataria extract
    Nepeta cataria extract can be used in health products for its antioxidant and antimicrobial properties.
    Nepeta cataria extract
  • HY-144341
    DprE1-IN-1
    		Inhibitor
    DprE1-IN-1 is a potent, orally active DprE1 inhibitor with favorable hepatocyte stability, low cytotoxicity and low hERG channel inhibition. DprE1-IN-1 displays potent activity against both agent-susceptible and clinically isolated drug-resistant Tuberculosis strains with MICs10 CFU reduction in macrophages.
    DprE1-IN-1
  • HY-147878
    Antibacterial agent 111
    		Inhibitor
    Antibacterial agent 111 (Compound 3) is an antibacterial agent with MIC values of 3.90 μg/mL and 0.49 μg/mL against B. cereus and K. pneumonia, respectively. Antibacterial agent 111 firmly binds with tyrosyl-tRNA synthetase residues.
    Antibacterial agent 111
  • HY-N18222
    Dihydroavicine
    		Inhibitor
    Dihydroavicine is a benzophenanthridine alkaloid antibacterial agent isolated from the stem bark of Zanthoxylum rhoifolium. Dihydroavicine inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, and Candida albicans. Dihydroavicine shows no activity against Saccharomyces cerevisiae and Cryptococcus neoformans. Dihydroavicine can be used for the research of bacterial infections and candidal infections.
    Dihydroavicine
  • HY-B1921
    Miocamycin
    		Inhibitor
    Miocamycin (Midecamycin acetate) is a derivative of midecamycin (HY-B1908), a macrolide antibiotic that can be isolated from a culture broth of Streptomyces mycarofaciens. Miocamycin has antibacterial properties.
    Miocamycin
  • HY-176234
    PDE4-IN-28
    		Inhibitor
    PDE4-IN-28 (Compound G1) is a PDE4D inhibitor (IC50: 29 nM). PDE4-IN-28 inhibits the production of TNF-α and NO (IC50: 13.32 and 2.32 μM, respectively). PDE4-IN-28 exhibits anti-inflammatory, antibacterial and analgesic effects in a rat pressure ulcer (PU) model and promotes HUVEC cell migration, thereby accelerating wound healing.
    PDE4-IN-28
  • HY-W725543
    Chlorphenesin-d5
    Chlorphenesin-d5 is the deuterium labeled Chlorphenesin (HY-A0133). Chlorphenesin is a reversible antigen-associated immunosuppressant. Chlorphenesin is an antibacterial and antifungal agent used in numerous eye care cosmetics.
    Chlorphenesin-d<sub>5</sub>
  • HY-N17457
    N-Demethyl-N-formyldehydronuciferine
    N-Demethyl-N-formyldehydronuciferine is a dehydroaporphine alkaloid. N-Demethyl-N-formyldehydronuciferine induces mutations in Salmonella typhimurium TA98 and TA100.
    N-Demethyl-N-formyldehydronuciferine
  • HY-132928
    Antitubercular agent-10
    		Inhibitor
    Antitubercular agent-10 shows potent antitubercular activity with a MIC value of 30 nM.
    Antitubercular agent-10
  • HY-162149
    Urease-IN-12
    		Inhibitor
    Urease-IN-12 (compound 5e) is a competitive urease inhibitor (IC50: 0.35 μM) with the potential to inhibit gastritis and peptic ulcer caused by Helicobacter pylori.
    Urease-IN-12
  • HY-P5693
    HBA(111–142)
    		Inhibitor
    HBA(111-142), an antimicrobial peptide, is a C-terminal 32-mer fragment of alpha-hemoglobin. HBA(111-142) has antibacterial activity against the ESKAPE panel of pathogens. HBA(111-142) forms amyloid fibrils, and has antiviral activities. HBA(111-142) inhibits measles and herpes viruses (HSV-1, HSV-2, HCMV).
    HBA(111–142)
  • HY-N8916
    Coulteropine
    		Inhibitor
    Coulteropine is a natural alkaloid with antimicrobial activities.
    Coulteropine
  • HY-161432
    Antimicrobial agent-29
    Antimicrobial agent-29 (Compound C35) affects the interaction between human hemoglobin and Staphylococcus aureus IsdB hemophore. Antimicrobial agent-29 helps the discovery of IsdB:Hb PPI inhibitors.
    Antimicrobial agent-29
  • HY-N11048
    Amycolatopsin A
    		Inhibitor
    Amycolatopsin A is a 20-membered macrolide, that can be isolated from a strain of the rare actinomycete Amycolatopsis sp. MST‐108494. Amycolatopsin A shows antimycobacterial activity against Mycobacterium bovis (BCG) and M. tuberculosis (H37Rv) with IC50 values of 0.4 µM and 4.4 µM, respectively.
    Amycolatopsin A
  • HY-151957
    Antitubercular agent 34
    		Inhibitor
    Antitubercular agent 34 (compound 42g) is an antitubercular agent. Antitubercular agent 34 inhibits the growth of MtbH37Rv with a MIC90 value of 1.25 μg/mL with the ability of escaping metabolic degradation by human liver microsomes. Antitubercular agent 34 can be used for the research of tuberculosis.
    Antitubercular agent 34
  • HY-131718
    (1-Isothiocyanatoethyl)benzene
    		Inhibitor
    (1-Isothiocyanatoethyl)benzene (compound 27) is an antimicrobial agent.
    (1-Isothiocyanatoethyl)benzene
  • HY-129285
    A83016A
    		Inhibitor
    A 83016A is a kinamycin-type antibiotic with the MIC of 4 ug/ml aganist En terococcus faecium.
    A83016A
  • HY-W751002
    Orthosporin
    		Inhibitor
    Orthosporin ((+)-Orthosporin), a phytotoxic isocoumarin compound, is a microbial secondary metabolite. Orthosporin can be isolated from the endophytic fungus Lasiodiplodia tbeobromae. Orthosporin has potent antibacterial activity against B. subtilis, E. coli and P. aeruginosa. Orthosporin also has antioxidant activity against DPPH radical and antiviral activities with inhibition of HIV-1 reverse transcriptase activity.
    Orthosporin
Cat. No. Product Name / Synonyms Application Reactivity