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Cat. No.: HY-N18222

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Dihydroavicine

Dihydroavicine is a benzophenanthridine alkaloid antibacterial agent isolated from the stem bark of Zanthoxylum rhoifolium. Dihydroavicine inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, and Candida albicans. Dihydroavicine shows no activity against Saccharomyces cerevisiae and Cryptococcus neoformans. Dihydroavicine can be used for the research of bacterial infections and candidal infections.

For research use only. We do not sell to patients.

CAS No.: 34490-82-9
Formula: C₂₀H₁₅NO₄
Molecular Weight:333.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Dihydroavicine Chemical Structure

CAS No.: 34490-82-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Dihydroavicine (compound 5) (1.56-12.5 μg; 24-72 h) inhibits the growth of specific Gram-positive bacteria, Gram-negative bacteria, and Candida albicans, with an effective inhibitory dose range of 1.56-12.5 μg against different microorganisms^[1].
Dihydroavicine (100 μg/mL; 24-72 h) exhibits weak antibacterial activity against specific Gram-positive and Gram-negative bacteria with an MIC of 100 μg/mL, but shows no activity against the tested yeasts^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability AssayWestern Blot AnalysisCell Proliferation AssayApoptosis AnalysisCell Cytotoxicity AssayCell Cycle AnalysisRT-PCRCell Autophagy AssayImmunofluorescenceCell Differentiation AssayCell Invasion AssayCell Migration Assay Real Time qPCRELISA Assay^[1]

Cell Line:

Gram-positive bacteria, Gram-negative bacteria, and the yeast Candida albicans
Concentration:

1.56-12.5 μg
Incubation Time:

24 h (bacteria); 72 h (yeast)
Result:

Exhibited effective inhibitory amounts ranging from 1.56 to 12.5 μg.

Chemical Information

CAS No. 34490-82-9
Molecular Weight 333.34
Formula C₂₀H₁₅NO₄
SMILES

CN1CC2=CC3=C(OCO3)C=C2C4=C1C5=CC6=C(C=C5C=C4)OCO6
Structure Classification
- Alkaloids
- Isoquinoline Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tavares Lde C, et al. Structure-activity relationship of benzophenanthridine alkaloids from Zanthoxylum rhoifolium having antimicrobial activity. PLoS One. 2014;9(5):e97000. Published 2014 May 13. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

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100 mg

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