2. Anti-infection
  3. Bacterial Fungal
  4. Dihydroavicine

Dihydroavicine is a benzophenanthridine alkaloid antibacterial agent isolated from the stem bark of Zanthoxylum rhoifolium. Dihydroavicine inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, and Candida albicans. Dihydroavicine shows no activity against Saccharomyces cerevisiae and Cryptococcus neoformans. Dihydroavicine can be used for the research of bacterial infections and candidal infections.

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Dihydroavicine

Dihydroavicine Chemical Structure

CAS No. : 34490-82-9

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Dihydroavicine Related Antibodies

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Description

Dihydroavicine is a benzophenanthridine alkaloid antibacterial agent isolated from the stem bark of Zanthoxylum rhoifolium. Dihydroavicine inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, and Candida albicans. Dihydroavicine shows no activity against Saccharomyces cerevisiae and Cryptococcus neoformans. Dihydroavicine can be used for the research of bacterial infections and candidal infections[1].

In Vitro

Dihydroavicine (compound 5) (1.56-12.5 μg; 24-72 h) inhibits the growth of specific Gram-positive bacteria, Gram-negative bacteria, and Candida albicans, with an effective inhibitory dose range of 1.56-12.5 μg against different microorganisms[1].
Dihydroavicine (100 μg/mL; 24-72 h) exhibits weak antibacterial activity against specific Gram-positive and Gram-negative bacteria with an MIC of 100 μg/mL, but shows no activity against the tested yeasts[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Dihydroavicine Related Antibodies

Cell Viability AssayWestern Blot AnalysisCell Proliferation AssayApoptosis AnalysisCell Cytotoxicity AssayCell Cycle AnalysisRT-PCRCell Autophagy AssayImmunofluorescenceCell Differentiation AssayCell Invasion AssayCell Migration Assay Real Time qPCRELISA Assay[1]

Cell Line: Gram-positive bacteria, Gram-negative bacteria, and the yeast Candida albicans
Concentration: 1.56-12.5 μg
Incubation Time: 24 h (bacteria); 72 h (yeast)
Result: Exhibited effective inhibitory amounts ranging from 1.56 to 12.5 μg.
Molecular Weight

333.34

Formula

C20H15NO4
CAS No.
SMILES

CN1CC2=CC3=C(OCO3)C=C2C4=C1C5=CC6=C(C=C5C=C4)OCO6
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Dihydroavicine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dihydroavicine34490-82-9BacterialFungalCryptococcus neoformansCandida albicansbacterial infectionfungal infectionSaccharomyces cerevisiaeZanthoxylum rhoifoliumGram-positive bacteriaGram-negative bacteriaInhibitorinhibitorinhibit

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