PDE4-IN-28
PDE4-IN-28 (Compound G1) is a PDE4D inhibitor (IC50: 29 nM). PDE4-IN-28 inhibits the production of TNF-α and NO (IC50: 13.32 and 2.32 μM, respectively). PDE4-IN-28 exhibits anti-inflammatory, antibacterial and analgesic effects in a rat pressure ulcer (PU) model and promotes HUVEC cell migration, thereby accelerating wound healing.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C28H27F2N9O6
- Peso molecular:623.57
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
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PDE4D 29 nM (IC50) |
Chemical Information
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Peso molecular 623.57
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Fòrmula C28H27F2N9O6
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SMILES
O=C1N(C2=C(C(N1C)=O)N(CCC(NNC(C3=NN4C(C5=CC(OCC6CC6)=C(C=C5)OC(F)F)=CC=NC4=C3)=O)=O)C=N2)C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PDE4-IN-28 Related Classifications
HY-176234 Related Classifications
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