1. Anti-infection
  2. Bacterial
  3. Antitubercular agent 34

Antitubercular agent 34 (compound 42g) is an antitubercular agent. Antitubercular agent 34 inhibits the growth of MtbH37Rv with a MIC90 value of 1.25 μg/mL with the ability of escaping metabolic degradation by human liver microsomes. Antitubercular agent 34 can be used for the research of tuberculosis.

For research use only. We do not sell to patients.

Antitubercular agent 34 Chemical Structure

Antitubercular agent 34 Chemical Structure

CAS No. : 2883173-23-5

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Description

Antitubercular agent 34 (compound 42g) is an antitubercular agent. Antitubercular agent 34 inhibits the growth of MtbH37Rv with a MIC90 value of 1.25 μg/mL with the ability of escaping metabolic degradation by human liver microsomes. Antitubercular agent 34 can be used for the research of tuberculosis[1].

In Vitro

Antitubercular agent 34 (0-20 μg/mL; 3-4 d) shows inhibitory effect to MtbH37Rv with a MIC90 value of 1.25 μg/mL[1].
Antitubercular agent 34 (0-100 μM; 3 d) shows inhibitory effect to human monocytes THP-I cell line[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: Human monocytes THP-I cell line
Concentration: 1, 10, 50 and 100 μM
Incubation Time: 72 hours
Result: Inhibited the growth of THP-I cells with an IC50 value of 11.9 μg/mL.
Molecular Weight

362.41

Formula

C19H14N4O2S

CAS No.
SMILES

O=C(C1=NOC(C2=CSC(NC3=CC=CC=C3)=N2)=C1)NC4=CC=CC=C4

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Antitubercular agent 34 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Antitubercular agent 34
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HY-151957
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