Amycolatopsin A
Amycolatopsin A is a 20-membered macrolide, that can be isolated from a strain of the rare actinomycete Amycolatopsis sp. MST‐108494. Amycolatopsin A shows antimycobacterial activity against Mycobacterium bovis (BCG) and M. tuberculosis (H37Rv) with IC50 values of 0.4 µM and 4.4 µM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 2209112-96-7
- Formula: C60H98O23
- Molecular Weight:1187.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Amycolatopsin A displays significant cytotoxicity against human colon carcinoma (SW620) and lung carcinoma (NCIH-460) cell lines with IC50 values of 0.08 µM and 1.2 µM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2209112-96-7
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Molecular Weight 1187.41
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Formula C60H98O23
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SMILES
C[C@]1([C@H](O[C@](O)([C@@H]([C@H]1O)OC)[C@@H](C2([H])CC(C(/C=C(/C=C(/C=C(C(C(/C=C(/C=C(\C=C(C(O2)=O)/C)OC)CO)C)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C)OC)O)O)/C)C)C)O)OC)C)CCCOC)O[C@H]4C[C@@H]([C@@H]([C@H](O4)C)O[C@H]5C[C@@](O)([C@@H]([C@H](O5)C)O)C)O
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Structure Classification
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Initial Source
Amycolatopsis sp.
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)