1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-125445
    PCTR1
    Inhibitor
    PCTR1 is a potent monocyte/macrophage agonist, regulating key anti-inflammatory and pro-resolving processes during bacterial infection. PCTR1 is a member of the protectin family of specialized pro-resolving mediators (SPMs).
    PCTR1
  • HY-147429A
    Zosurabalpin TFA
    Inhibitor
    Zosurabalpin TFA is a tethered macrocyclic peptide antibiotic, acting specifically on A. baumannii. Zosurabalpin TFA inhibits lipopolysaccharide-transport.
    Zosurabalpin TFA
  • HY-151552
    Mtb-cyt-bd oxidase-IN-5
    Inhibitor
    Mtb-cyt-bd oxidase-IN-5 (compound 1k) is a Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase (MtbCyt-bd Oxidase) inhibitor with an IC50 value of 0.37 μM. Mtb-cyt-bd oxidase-IN-5 can effectively inhibit the growth of Mtb (MIC= 256 μM). Mtb-cyt-bd oxidase-IN-5 can be used in the study of tuberculosis.
    Mtb-cyt-bd oxidase-IN-5
  • HY-N18249
    Rehmaglupentasaccharide A
    Rehmaglupentasaccharide A is a pentasaccharide found in air-dried roots of Rehmannia glutinosa. Rehmaglupentasaccharide A promotes proliferation of Lactobacillus reuteri.
    Rehmaglupentasaccharide A
  • HY-N8089
    Bis(dihydrochelerythrinyl)amine
    Inhibitor
    Bis(dihydrochelerythrinyl)amine possesses anti-bacteria activity.
    Bis(dihydrochelerythrinyl)amine
  • HY-126929
    Trioxacarcin B
    Inhibitor
    Trioxacarcin B (TXN-B) is a potent cytotoxic agent and DNA-targeted inhibitor. Trioxacarcin B disrupts DNA function and induces apoptosis in cancer cells. Trioxacarcin B not only effectively inhibits the growth of various Gram-positive and Gram-negative bacteria as well as Plasmodium falciparum, but also blocks the colony formation of cancer stem cells, significantly reduces tumor volume and prolongs survival in preclinical in vivo models. The activity of Trioxacarcin B is highly dependent on its intact spiro-epoxide structure; it loses efficacy once this moiety undergoes hydrolysis, and Trioxacarcin B shows no activity against fungi, microalgae and small RNA viruses. Trioxacarcin B can be used for research on bacterial infections, malaria, and various cancers including colon cancer and melanoma.
    Trioxacarcin B
  • HY-W010520R
    Methylisothiazolinone (Standard)
    Inhibitor
    Methylisothiazolinone (Standard) is the analytical standard of Methylisothiazolinone. Methylothiazolinone is a fungicide and preservative, as well as a sensitizer. Methylisothiazolinone can activate matrix metalloproteinases (MMPs) in human bronchial epithelial cells to induce cell apoptosis and inflammatory response. Methylisothiazolinone can promote the development of atopic dermatitis in mice by disrupting Th2/Th17 related immune responses. Methylisothiazolinone can cause mitochondrial damage in the endothelium of rat cerebral blood vessels.
    Methylisothiazolinone (Standard)
  • HY-N6748S
    Roquefortine C-13C22
    Roquefortine C-13C22 is the 13C-labeled Roquefortine C (HY-N6748). Roquefortine C is a mycotoxin that can be isolated from Penicillium species. Roquefortine C is an agonist of P-gp and an inhibitor of P450 3A and P450 1A. Roquefortine C can inhibit Gram-positive bacteria and also has certain neurotoxicity. Additionally, Roquefortine C can exert antitumor activity.
    Roquefortine C-<sup>13</sup>C<sub>22</sub>
  • HY-66004R
    4-Acetamidophenyl acetate (Standard)
    4-Acetamidophenyl acetate (Standard) is the analytical standard of 4-Acetamidophenyl acetate (HY-66004). This product is intended for research and analytical applications. 4-Acetamidophenyl acetate is an impurity of Acetaminophen (HY-66005). 4-Acetamidophenyl acetate acts as an intermediate in the synthesis of Acetaminophen. Acetaminophen is a selective COX-2 inhibitor (IC50=25.8 μM), and is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
    4-Acetamidophenyl acetate (Standard)
  • HY-151373
    MurA-IN-2
    Inhibitor
    MurA-IN-2 (compound 37), a chloroacetamide fragment containing a primary aliphatic amine, is a potent MurA inhibitor with an IC50 value of 39 μM. MurA-IN-2 has antibacterial activity and inhibits the bacterial cell wall synthesis.
    MurA-IN-2
  • HY-P5708
    Adenoregulin
    Inhibitor
    Adenoregulin (Dermaseptin b2) is an antimicrobial peptide antibiotic. Adenoregulin is active against Gram-negative and Gram-positive bacteria, yeast and fungi. Adenoregulin also enhances the binding of agonists to the A1 adenosine receptor.
    Adenoregulin
  • HY-183792
    Antibacterial agent 347
    Inhibitor
    Antibacterial agent 347 is an Antibacterial agent. Antibacterial agent 347 exhibits selective antibacterial activity against Streptococcus mutans. Antibacterial agent 347 shows moderate ABTS•+ free radical scavenging activity.
    Antibacterial agent 347
  • HY-170386
    TXY541
    Inhibitor
    TXY541 is an orally active antibacterial agent that can be converted to PC190723 (HY-146331) under physiological conditions. TXY541 has good antibacterial effect against Staphylococcus aureus and low toxicity to mammalian cells.
    TXY541
  • HY-151875
    MurA-IN-3
    Inhibitor
    MurA-IN-3 is a reversible pyrrolidinedione-based MurA inhibitor. MurA-IN-3 has inhibitory activity for MurA with an IC50 value of 4.5 μM. MurA-IN-3 also has antibacterial activity.
    MurA-IN-3
  • HY-108279S
    Ulifloxacin-d8
    Inhibitor 99.22%
    Ulifloxacin-d8 is the deuterium labeled Ulifloxacin (HY-108279). Ulifloxacin is a broad-spectrum quinolone antibiotic. Ulifloxacin is the active metabolite of Prulifloxacin (HY-B0024). Ulifloxacin has anti-bacterial activity.
    Ulifloxacin-d<sub>8</sub>
  • HY-113289R
    Brassicasterol (Standard)
    Inhibitor
    L-Ornithine (hydrochloride) (Standard) is the analytical standard of L-Ornithine (hydrochloride). This product is intended for research and analytical applications. L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective.
    Brassicasterol (Standard)
  • HY-17577R
    Berberine chloride hydrate (Standard)
    Inhibitor
    Berberine (chloride hydrate) (Standard) is the analytical standard of Berberine (chloride hydrate). This product is intended for research and analytical applications. Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid that acts as an antibiotic. Berberine chloride hydrate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties[1].
    Berberine chloride hydrate (Standard)
  • HY-144279
    MsbA-IN-1
    MsbA-IN-1 is a highly potent MsbA inhibitor with IC50 of 4 nM. MsbA-IN-1 has activity against wild-type E. coli with MIC of 79 μM. MsbA-IN-1 possesses sufficient permeability across the fully intact outer membrane of Gram-negative bacteria to inhibit MsbA.
    MsbA-IN-1
  • HY-N7449R
    Neamine (Standard)
    Inhibitor
    Neamine, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities.
    Neamine (Standard)
  • HY-151357
    MraY-IN-3
    Inhibitor
    MraY-IN-3 (12a) is a potent bacterial translocase MraY inhibitor with an IC50 value of 140 µM. MraY-IN-3 acts on E. coli K12, B. subtilis W23 and P. fluorescens Pf-5 with the MIC50 values of 7 µg/mL, 12 µg/mL, and 46 µg/mL, respectively.
    MraY-IN-3
Cat. No. Product Name / Synonyms Application Reactivity