MurA-IN-3
MurA-IN-3 is a reversible pyrrolidinedione-based MurA inhibitor. MurA-IN-3 has inhibitory activity for MurA with an IC50 value of 4.5 μM. MurA-IN-3 also has antibacterial activity.
For research use only. We do not sell to patients.
- CAS No.: 2866186-38-9
- Formula: C27H23ClN2O5S
- Molecular Weight:523.00
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 4.5 μM (MurA); 4.9 μM (C115D MurA mutant)[1].
MurA-IN-3 has inhibitory activity for MurA and C115D MurA mutant with IC50 values of 4.5 μM and 4.9 μM, respectively[1].
MurA-IN-3 (0-100 μM; 24 h) has no cytotoxicity on both MRC-5 and HepG2 cell lines[1].
MurA-IN-3 has antibacterial activity and pronounced stability[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2866186-38-9
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Molecular Weight 523.00
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Formula C27H23ClN2O5S
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SMILES
CC1=CC=C2N=C(SC2=C1)N3C(C(O)=C(C3C4=CC=C(O4)C5=CC=C(C=C5)Cl)C(OC(C)(C)C)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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