1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-118946A
    BPH-1358 free base
    Inhibitor
    BPH-1358 free base (NSC50460 free base) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor with IC50s of 1.8 μM and 110 nM, respectively, and is active against S. aureus in vitro (MIC ~250 ng/mL).
    BPH-1358 free base
  • HY-D2730
    N14G-Fe
    Inhibitor
    N14G-Fe, the Fe3+-chelated form of N14G, identifies Mtb in sputum samples with tuberculosis, exhibiting exceptional fluorescence. N14G-Fe can effectively traverse the cell wall and inner membrane region where IrtAB is located.
    N14G-Fe
  • HY-154861
    Anticancer agent 118
    Inhibitor
    Anticancer agent 118, a N‑acylated ciprofloxacin derivative, has anti-bacterial and anticancer activities. Anticancer agent 118 shows high activity against Gram-positive strains and antiproliferative activities against prostate PC3 cells. Anticancer agent 118 can be used for antitumor research.
    Anticancer agent 118
  • HY-126866
    Lankacidin C 8-acetate
    Inhibitor
    Lankacidin C 8-acetate is an antibiotic with antibacterial activity. Lankacidin C 8-acetate, as a component of the Lankacidin group (T-2636) antibiotics, shows inhibitory effects against specific bacteria. Lankacidin C 8-acetate can generate other esterates by reacting with different acyl donors, indicating its importance in the synthesis of antibiotics.
    Lankacidin C 8-acetate
  • HY-121136
    Chartreusin
    Inhibitor
    Chartreusin is an antibiotic that is active against certain Gram-positive organisms and mycobacteria. Chartreusin is also active against the Micrococcus fiyogenes v. aureus phage.
    Chartreusin
  • HY-107996
    Lapyrium chloride
    Inhibitor
    Lapyrium chloride (Emcol E 607) is a broad-spectrum antimicrobial agent that can be used as an antiseptic and disinfectant.
    Lapyrium chloride
  • HY-W011117S
    Danofloxacin-d3
    Inhibitor
    Danofloxacin-d3 is deuterium labeled Danofloxacin. Danofloxacin is an orally active quinolone antibiotic. Danofloxacin targets bacterial DNA gyrase and inhibits bacterial DNA replication, transcription and growth. Danofloxacin can be used for various bacterial infections caused by Escherichia coli, Mycoplasma and other pathogens.
    Danofloxacin-d<sub>3</sub>
  • HY-107313
    Macranthoside A
    Inhibitor 99.47%
    Macranthoside A is a triterpene glycoside with anti-microbially activity.
    Macranthoside A
  • HY-B0502AS
    Enrofloxacin-d5 hydrochloride
    Inhibitor
    Enrofloxacin-d5 (hydrochloride) is deuterium labeled Enrofloxacin (monohydrochloride). Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis.
    Enrofloxacin-d<sub>5</sub> hydrochloride
  • HY-122262
    NDM-1-IN-6
    Inhibitor
    NDM-1-IN-6 (Compound 1) is a potent, selective and competitive New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor with a Ki of 0.72 μM. NDM-1-IN-6 has a synergistic antibacterial effect with the carbapenem antibiotic Meropenem (HY-13678). NDM-1-IN-6 is mainly used for research on NDM-1-mediated multidrug-resistant bacterial infections.
    NDM-1-IN-6
  • HY-15398S1
    Vitamin D3-13C3
    Vitamin D3-13C3 is the 13C-labeled Vitamin D3. Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
    Vitamin D3-<sup>13</sup>C<sub>3</sub>
  • HY-172749
    IMCTA-C14 TFA
    Inhibitor
    IMCTA-C14 TFA, a trehalose analog, is a detergent. IMCTA-C14 TFA shows autophagy-inducing activity in OVK18 cells and can be effectively used in membrane protein research. IMCTA-C14 TFA is active against various bacteria (MICs = 8-128 µg/mL) and is cytotoxic against cancer cell lines (IC50s = 2.9-29.2 µg/mL).
    IMCTA-C14 TFA
  • HY-N19420
    Theasinensin C
    Modulator
    Theasinensin C is an orally effective renin inhibitor and gut microbiota modulator, with an IC50 of 40.21 μM against renin activity. Theasinensin C selectively enriches Akkermansia muciniphila in the gut microbiota, enhances the Akkermansia muciniphila-mediated hydrolysis of the PTS domain of mucin, drives the accumulation of luminal glutamine and serine, and regulates the gut-kidney-liver glutamine/serine metabolic signaling pathway to promote creatine biosynthesis. Theasinensin C improves cognitive function, reduces pro-inflammatory cytokines, alleviates neuropathological changes and restores intestinal barrier integrity. Theasinensin C can be used in research related to hypertension and neuroinflammation induced by high-fructose diet.
    Theasinensin C
  • HY-117736
    Ro 09-1428
    Inhibitor
    Ro 09-1428 is a broad-spectrum parenteral cephalosporin. Ro 09-1428 has potent antibacterial activities against Pseudomonas aeruginosa and Acinetobacter caloaceticus, with MIC90s of 0.39 and 6.25 μg/mL, respectively, better than Ceftazidime (HY-B0593). Additionally, Ro 09-1428 shows high activity against Escherichia coli, Kkbsielia pneumoniae, Proteus mirabilis, P. aeruginosa, staphylococci, and more. Ro 09-1428 preferentially attacks PBP 3 for target in E. coli and P. aeruginosa, which is promising for research of septicemias and serious P. aeruginosa infections.
    Ro 09-1428
  • HY-108138
    FCE-25199
    Inhibitor
    FCE-25199 is an orally active penem antibiotic. FCE-25199 has antibacterial activity against various Gram positive and Gram negative bacteria. FCE-25199 is commonly used in the study of bacterial infections.
    FCE-25199
  • HY-114509R
    Anilazine (Standard)
    Inhibitor
    Anilazine (Standard) is the analytical standard of Anilazine. This product is intended for research and analytical applications. Anilazine is a fungicide and inhibit the growth of Rhizobium sp. and E. coli. Anilazine inhibits glucose oxidation and succinate oxidation and also inhibits in vitro succinic dehydrogenase activity.
    Anilazine (Standard)
  • HY-P5652
    Bombolitin II
    Bombolitin II is an antimicrobial peptide derived from bumblebee venom. Bombolitin II can lysate erythrocyte and liposome.
    Bombolitin II
  • HY-155511
    DprE1-IN-6
    Inhibitor
    DprE1-IN-6 (Compound 56) is a DprE1 inhibitor. DprE1-IN-6 has anti-TB activity against Mtb H37Rv strain (MIC: 1 μM). DprE1-IN-6 also has antimycobacterial activity against drug-resistant strains. DprE1-IN-6 has high microsomal stability and medium clearance.
    DprE1-IN-6
  • HY-182267
    Antibiofilm agent-20
    Inhibitor
    Antibiofilm agent-20 is an orally active Escherichia coli biofilm inhibitor (IC50 = 5.5 μg/mL) and show low antibacterial activity (MIC >128 μg/mL). Antibiofilm agent-20 exhibits high lipophilicity and low solubility, resulting in low colon delivery rate. Antibiofilm agent-20 demonstrates anti-inflammatory and reduces IL-17 and TNF-α levels. Antibiofilm agent-20 can be used for the research of inflammatory bowel disease.
    Antibiofilm agent-20
  • HY-B1781A
    Sulfachloropyridazine sodium
    Inhibitor 99.34%
    Sulfachloropyridazine (sodium) is a sulfonamide antibiotic that inhibits bacterial growth.
    Sulfachloropyridazine sodium
Cat. No. Product Name / Synonyms Application Reactivity