N14G-Fe
N14G-Fe, the Fe3+-chelated form of N14G, identifies Mtb in sputum samples with tuberculosis, exhibiting exceptional fluorescence. N14G-Fe can effectively traverse the cell wall and inner membrane region where IrtAB is located.
For research use only. We do not sell to patients.
- Formula: C76H103ClFeN11O133+
- Molecular Weight:1469.99
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
N14G-Fe (0.1 μM, 1 h, red) can detect Mycobacterium smegmatis at concentrations as low as 1−10 nM within an incubation period of less than 5 min[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 1469.99
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Formula C76H103ClFeN11O133+
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SMILES
>>O=C(N[C@@H](C)[C@@H](C(N[C@@H]1C(N([O])CCCC1)=O)=O)NC(CCC(N2CCN(C(C3=C(C4=C(C=C/5)C(OC6=C4C=CC(N(CC)CC)=C6)=CC5=[N+](CC)\CC)C=CC=C3)=O)CC2)=O)=O)[C@H](CCCCN([O])C(CCCCCCCCCCCCC)=O)NC([C@H](CO7)N=C7C8=C([O])C=CC=C8)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Dianmo Ni, et al. Insights into IrtAB: Iron Transport Facilitates Ultrasensitive Detection of Mycobacteria in Both Cellular and Clinical Environments. ACS Cent Sci. 2025 Jan 7;11(2):261-271. [Content Brief]
[2]. Abdulai Zigli, et al. Pumping Iron for Tuberculosis Diagnostics. ACS Cent Sci. 2025 Feb 11;11(2):190-192. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)