Danofloxacin-d3
Danofloxacin-d3 is deuterium labeled Danofloxacin. Danofloxacin is an orally active quinolone antibiotic. Danofloxacin targets bacterial DNA gyrase and inhibits bacterial DNA replication, transcription and growth. Danofloxacin can be used for various bacterial infections caused by Escherichia coli, Mycoplasma and other pathogens.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 1825377-28-3
- Formel: C19H17D3FN3O3
- Molecular Weight:360.40
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Beschreibung
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 1825377-28-3
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Unlabeled CAS 112398-08-0
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Molecular Weight 360.40
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Formel C19H17D3FN3O3
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SMILES
O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4[C@](C5)([H])CN(C([2H])([2H])[2H])[C@]5([H])C4)=C3)C1=O)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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PCNA Immunodetection Proliferation Assay
PCNA immunodetection measures proliferative activity by detecting proliferating cell nuclear antigen, a nuclear protein associated with DNA polymerase δ function and DNA replication. The assay readout is the proportion of PCNA-positive nuclei among total counted cells, but PCNA labeling is not identical to BrdU labeling because PCNA can mark late G1/early S-associated replication competence and may persist beyond active DNA synthesis depending on fixation and extraction conditions.
Reinheit & Dokumentation
Verweise
[1]. Erjie Tian, et al. Population Pharmacokinetics for Danofloxacin in the Intestinal Contents of Healthy and Infected Chickens. J Vet Pharmacol Ther. 2019 Sep;42(5):556-563. [Content Brief]
[2]. Xia Xiao, et al. Comparative Pharmacokinetics of Danofloxacin in Healthy and Pasteurella Multocida Infected Ducks. J Vet Pharmacol Ther. 2018 Dec;41(6):912-918. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Danofloxacin-d3 Related Classifications
HY-W011117S Related Classifications
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