112398-08-0
Chemical Structure
Danofloxacin
- CAS No.: 112398-08-0
- Formula:C19H20FN3O3
- Molecular Weight:357.38
IUPAC Name: 1-cyclopropyl-6-fluoro-7-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
InChIKey: QMLVECGLEOSESV-RYUDHWBXSA-N
SMILES: O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4[C@](C5)([H])CN(C)[C@]5([H])C4)=C3)C1=O)O
Biological Activity: Danofloxacin is an orally active quinolone antibiotic. Danofloxacin targets bacterial DNA gyrase and inhibits bacterial DNA replication, transcription and growth. Danofloxacin can be used for various bacterial infections caused by Escherichia coli, Mycoplasma and other pathogens[1][2][3].
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Danofloxacin | 98.56% | Danofloxacin is an orally active quinolone antibiotic. Danofloxacin targets bacterial DNA gyrase and inhibits bacterial DNA replication, transcription and growth. Danofloxacin can be used for various bacterial infections caused by Escherichia coli, Mycoplasma and other pathogens. | ||||||||||||||||||||
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Danofloxacin (Standard) | ≥98% | Danofloxacin (Standard) is the analytical standard of Danofloxacin. This product is intended for research and analytical applications. Danofloxacin is an orally active quinolone antibiotic. Danofloxacin targets bacterial DNA gyrase and inhibits bacterial DNA replication, transcription and growth. Danofloxacin can be used for various bacterial infections caused by Escherichia coli, Mycoplasma and other pathogens. | ||||||||||||||||||||
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Danofloxacin-d3 | Danofloxacin-d3 is deuterium labeled Danofloxacin. Danofloxacin is an orally active quinolone antibiotic. Danofloxacin targets bacterial DNA gyrase and inhibits bacterial DNA replication, transcription and growth. Danofloxacin can be used for various bacterial infections caused by Escherichia coli, Mycoplasma and other pathogens. | |||||||||||||||||||||
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Danofloxacin-d3-1 | 99.85% | Danofloxacin-d3-1 is deuterium labeled Danofloxacin. Danofloxacin is an orally active quinolone antibiotic. Danofloxacin targets bacterial DNA gyrase and inhibits bacterial DNA replication, transcription and growth. Danofloxacin can be used for various bacterial infections caused by Escherichia coli, Mycoplasma and other pathogens. | ||||||||||||||||||||
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- [1]. Chen JC, et al. In vitro antibacterial activity of danofloxacin against Escherichia coli in Gushi chickens and its residue depletion following multiple oral administration. Poult Sci. 2024;103(4):103493. [Content Brief]
- [2]. Tian E, et al. Population pharmacokinetics for danofloxacin in the intestinal contents of healthy and infected chickens. J Vet Pharmacol Ther. 2019;42(5):556-563. [Content Brief]
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[3]. Yang Y, et al. Susceptibility breakpoint for Danofloxacin against swine Escherichia coli. BMC Vet Res. 2019 Feb 4;15(1):51.
[Content Brief]
