Danofloxacin-d3 mesylate
Danofloxacin-d3 (mesylate) is the deuterium labeled Danofloxacin mesylate. Danofloxacin mesylate (CP 76136-27) is a fluoroquinolone antibacterial for veterinary use.
For research use only. We do not sell to patients.
- CAS No.: 1217860-94-0
- Formula: C20H21D3FN3O6S
- Molecular Weight:456.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1217860-94-0
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Unlabeled Cas 119478-55-6
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Molecular Weight 456.50
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Formula C20H21D3FN3O6S
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SMILES
CS(=O)(O)=O.O=C1C2=CC(F)=C(N3[C@H]4C[C@H](N(C4)C([2H])([2H])[2H])C3)C=C2N(C5CC5)C=C1C(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Giles, C.J., et al., Clinical pharmacokinetics of parenterally administered danofloxacin in cattle. J Vet Pharmacol Ther, 1991. 14(4): p. 400-10. [Content Brief]
[3]. McGuirk, P.R., et al., Synthesis and structure-activity relationships of 7-diazabicycloalkylquinolones, including danofloxacin, a new quinolone antibacterial agent for veterinary medicine. J Med Chem, 1992. 35(4): p. 611-20. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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