Fungal

Related Products

An antifungal agent is a drug that selectively eliminates fungal pathogens from a host with minimal toxicity to the host.

Classes: 1. Polyene Antifungal Drugs: Amphotericin, nystatin, and pimaricin interact with sterols in the cell membrane (ergosterol in fungi, cholesterol in humans) to form channels through which small molecules leak from the inside of the fungal cell to the outside. 2. Azole Antifungal Drugs: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. 3. Allylamine and Morpholine Antifungal Drugs: lylamines (naftifine, terbinafine) inhibit ergosterol biosynthesis at the level of squalene epoxidase. The morpholine drug, amorolfine, inhibits the same pathway at a later step. 4. Antimetabolite Antifungal Drugs: 5-Fluorocytosine acts as an inhibitor of both DNA and RNA synthesis via the intracytoplasmic conversion of 5-fluorocytosine to 5-fluorouracil.

Fungal Related Products (2623)
Antibodies (1)
Related Compound Screening Libraries (1)

By Effects:	Inhibitors (2336)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-161921

Antifungal agent 108	Inhibitor
Antifungal agent 108 (compound 14d), an original imidazo[1,2-b]pyridazine derivative, shows potent antifungal activity against Madurella mycetomatis (MM55 strain) with an IC₅₀ of 0.9 μM. Antifungal agent 108 exhibits an IC₅₀ of 14.3 μM on cell viability of NIH-3T3 murine fibroblast.

HY-B2061

Vinclozolin	Inhibitor	98.47%
Vinclozolin is a non-systemic dicarboximide fungicide. Vinclozolin is also an antagonist of the androgen receptor, exerting anti-androgenic effects through its metabolites. Vinclozolin inhibits spore germination and can be used to control fungi in plants such as vegetables and fruits. Vinclozolin is toxic to the reproductive system of rats and possesses certain anti-tumor activity.

HY-P11398

Tachyplesin II	Inhibitor
Tachyplesin II is a broad-spectrum cationic antimicrobial peptide. Tachyplesin II has significant inhibitory effects on Gram-positive bacteria, Gram-negative bacteria, and some fungi. Tachyplesin II binds to bacterial membrane lipopolysaccharides through its positive charge, disrupting membrane integrity and causing leakage of cellular contents. Tachyplesin II can bind to DNA grooves, inhibiting microbial replication, and also suppressing HIV-1 replication and the proliferation of liver cancer cells.

HY-123510

NSC-670224	Inhibitor
NSC-670224 is toxic to Saccharomyces cerevisiae at low micromolar concentration (LC₅₀: 3.2 μM).

HY-184209

Antifungal agent-163	Inhibitor
Antifungal agent-163 is an antifungal agent. Antifungal agent-163 inhibits the activity of coenzyme Q-cytochrome C reductase (CoQ-Ccr), thereby disrupting electron transport in the mitochondrial respiratory chain. Antifungal agent-163 induces intracellular ROS accumulation, causes cell membrane damage, and impairs mitochondrial function in Sublineola cells. Antifungal agent-163 exhibits control effects against fungal plant diseases. Antifungal agent-163 can be used in the research of sorghum anthracnose.

HY-N7123S1

Sulfacetamide-¹³C₆	Inhibitor
Sulfacetamide-¹³C₆ (Sulphacetamide¹³C₆) is the ¹³C₆ labeled Sulfacetamide (HY-N7123). Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide has antifungal and antibacterial activities.

HY-136355S

Picoxystrobin-d₃	Inhibitor
Picoxystrobin-d₃ is the deuterium labeled Picoxystrobin (HY-136355). Picoxystrobin is a strobilurin fungicide. Picoxystrobin controls plant diseases by inhibiting mitochondrial respiration. Picoxystrobin is highly toxic to zebrafish embryos, causing developmental abnormalities, oxidative stress, and immunotoxicity.

HY-B2026

Propamocarb	Inhibitor
Propamocarb is a systemic fungicide. Propamocarb is widely used to protect cucumbers, tomatoes and other plants from pathogens.

HY-178088

L-731120	Inhibitor
L-731120 is an alkyl citrate zargozaga acid A analogue, which is secondary metabolite produced by fungal fermentation. L-731120 shows inhibitory activity against squalene synthase (SQS) (IC₅₀ = 260 nM). L-731120 can inhibit the synthesis of cholesterol in the liver. L-731120 can be used for the research of infection and metabolic disease, such as hypercholesterolemia.

HY-N12682

Phoslactomycin C	Inhibitor
Phoslactomycin C has weak effect against Gram-positive bacteria, but has strong effect against fungi.

HY-N17760

(25RS)-Schidigera-saponin E1	Inhibitor
(25RS)-Schidigera-saponin E1 is a steroidal saponin with anti-yeast activity, which can be isolated from the stems of Yucca schidigera (Mojave yucca). (25RS)-Schidigera-saponin E1 exerts weak anti-yeast activity by affecting the integrity of microbial cell membranes, with a MIC≥100 μg/mL against some food spoilage yeasts. (25RS)-Schidigera-saponin E1 can be used in the field of food preservation to extend the shelf life of foods containing cooked rice, beans, fermented condiments, etc.

HY-N1289

Sequosempervirin B	Inhibitor
Sequosempervirin B, a norlignan isolated from the branches and leaves of Sequoia sempervirens, has antifungal properties. Sequosempervirin B has an inhibitory effect on cyclic AMP phosphodiesterase.

HY-151423

Antifungal agent 39	Inhibitor
Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent.

HY-N0415R

Trigonelline chloride (Standard)	Inhibitor
Trigonelline (chloride) (Standard) is the analytical standard of Trigonelline (chloride). This product is intended for research and analytical applications. Trigonelline chloride is an alkaloid with potential antidiabetic activity that can be isolated from Trigonella foenum-graecum L or Leonurus artemisia. Trigonelline chloride is a potent Nrf2 inhibitor that blocks Nrf2-dependent proteasome activity, thereby enhancing apoptosis in pancreatic cancer cells. Trigonelline chloride also has anti-HSV-1, antibacterial, and antifungal activity, and induces ferroptosis.

HY-123155

Pyrimorph	Inhibitor
Pyrimorph is a fungicide with excellent antifungal activity against oomycetes.

HY-133169

Topazolin	Inhibitor
Topazolin is a flavone. Topazolin has weak fungi-toxic activity against Cladosporium herbarum AHU 9262.

HY-N10611

Elsinochrome A	Inhibitor
Elsinochrome A is a perylene quinone photosensitizer, and can generate reactive oxygen species (ROS) to induce apoptosis and autophagy under light excitation. Elsinochrome A also shows antifungal activity against C. albicans biofilm through photodynamic antimicrobial chemotherapy (PACT). Elsinochrome A can be used for research of photodynamic therapy (PDT) (Ex: 460 nm).

HY-N7519

5-(12Z-Heptadecenyl)-resorcinol	Inhibitor
5-(12Z-Heptadecenyl)-resorcinol serves as the main component of Antifungal mixtures. 5-(12Z-Heptadecenyl)-resorcinol can be isolated from mango peels. Antifungal mixtures composed of 5-(12Z-Heptadecenyl)-resorcinol exhibit activity against Alternaria alternata. 5-(12Z-Heptadecenyl)-resorcinol can be used in studies related to mango fruit black spot disease.

HY-W116336B

Zinc oxide, 99.99% metals basis	Inhibitor	99.99%
Zinc oxide, 99.99% metals basis is a versatile wide-bandgap semiconductor with superior comprehensive properties. Zinc oxide, 99.99% metals basis serves as raw material for Schottky diodes, functional nanostructures, sensors, energy harvesters and photocatalysts for hydrogen production. Zinc oxide, 99.99% metals basis acts as a non-toxic antibacterial agent and selective cytotoxin against multiple bacteria, fungi and spores. Zinc oxide, 99.99% metals basis induces cancer cell death. Zinc oxide, 99.99% metals basis is applicable to drug delivery, biosensing, bioimaging and researches on cancer, microbial infections and skin diseases.

HY-B0996R

Hexetidine (Standard)	Inhibitor
Hexetidine (Standard) is the analytical standard of Hexetidine. This product is intended for research and analytical applications. Hexetidine is an orally active antiseptic with broad antibacterial and antifungal activity. Hexetidine give important potential for treatment of oral infections.

Antifungal Compound Library

Compound library containing all kinds of molecules with anti-fungal activity.

559compounds HY-L048

Name
Email *

	Sorry, but the email address you supplied was invalid.

Fungal

Fungal

Fungal Related Products (2623)

Antibodies (1)

Related Compound Screening Libraries (1)

Fungal Related Products (2623):