Propamocarb

Propamocarb significantly induces the expression of PAL, POD, CYP, AMP, ANP, and UDP genes in cucumber fruit peel, with the highest induction for POD reaching a 70.83-fold increase at 6 h post-treatment^[1].
Propamocarb significantly increases the activities of PAL (to 101.8 nmol·h^-1·mg^-1 protein) and POD (to 106.1 U·g^-1 FW) in cucumber fruit peel^[1].
Propamocarb significantly increases acetylbromide-extractable Lignin (HY-111830) content in cucumber fruit peel, reaching 80.76 mg/g dry weight, which is a 41.1% increase compared to the control^[1].
Propamocarb (1.8-10 mg/mL; 5-7 days) provided minimal inhibition of mycelial growth for the 71 P. nicotianae isolates tested, with the most sensitive isolate showing 34.8% relative growth at 10 mg/mL^[2].
Propamocarb (1-100 mg/mL; 5-7 days) is a poor inhibitor of P. nicotianae mycelial growth, with EC₅₀ values ranging from 2.2 to 90.1 mg/mL across the nine isolates and a mean of 20.6 mg/mL^[2].
Propamocarb (5-50,000 µg/mL; 10 h) potently suppressed sporangium production in P. nicotianae isolates, with EC₅₀ values ranging from 133.8 to 481.3 µg/mL and complete inhibition at 50,000 µg/mL^[2].
Propamocarb (5-50,000 µg/mL; 10 min-1 h) inhibited zoospore motility in P. nicotianae isolates, with EC₅₀ values ranging from 88.1 to 249.8 µg/mL and complete cessation of motility within 10 min at 5,000 µg/mL or above^[2].
Propamocarb (5-50,000 µg/mL; 2 days) inhibited zoospore germination in P. nicotianae isolates, with EC₅₀ values ranging from 1.9 to 184.6 µg/mL across the nine isolates^[2].
Propamocarb (0.1-50 µg/mL; 7 days) slightly affected cell viability and moderately reduced mitochondrial function, glucose consumption, and intracellular ATP in primary rat cortical neurons, with these effects being strongly mitigated or completely prevented by pyruvate and acetylcysteine supplementation; the compound showed no direct effect on GSH levels within 1 h^[5].
Propamocarb controls late blight in detached potato leaves incited by P. infestans with EC₉₀ values ranging from 72 to 122 ppm, with no significant difference between Metalaxyl (HY-B0843)-sensitive and metalaxyl-resistant isolates^[6].