Vinclozolin
Based on 1 Customer Validation
Vinclozolin is a non-systemic dicarboximide fungicide. Vinclozolin is also an antagonist of the androgen receptor, exerting anti-androgenic effects through its metabolites. Vinclozolin inhibits spore germination and can be used to control fungi in plants such as vegetables and fruits. Vinclozolin is toxic to the reproductive system of rats and possesses certain anti-tumor activity.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.47%
- CAS. Nr.: 50471-44-8
- Formel: C12H9Cl2NO3
- Molecular Weight:286.11
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 50471-44-8
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Appearance Solid
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Molecular Weight 286.11
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Formel C12H9Cl2NO3
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Color White to light yellow
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SMILES
O=C(N1C2=CC(Cl)=CC(Cl)=C2)OC(C)(C=C)C1=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (349.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Reinheit & Dokumentation
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Data Sheet (274 KB)
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SDS (761 KB)
- English - EN (761 KB)
- Français - FR (761 KB)
- Deutsch - DE (761 KB)
- Norwegian - NO (761 KB)
- Español - ES (761 KB)
- Swedish - SV (761 KB)
- Italian - IT (761 KB)
- Korean - KR (761 KB)
- Portuguese - PT (761 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4952 mL | 17.4758 mL | 34.9516 mL | 87.3790 mL |
| 5 mM | 0.6990 mL | 3.4952 mL | 6.9903 mL | 17.4758 mL | |
| 10 mM | 0.3495 mL | 1.7476 mL | 3.4952 mL | 8.7379 mL | |
| 15 mM | 0.2330 mL | 1.1651 mL | 2.3301 mL | 5.8253 mL | |
| 20 mM | 0.1748 mL | 0.8738 mL | 1.7476 mL | 4.3689 mL | |
| 25 mM | 0.1398 mL | 0.6990 mL | 1.3981 mL | 3.4952 mL | |
| 30 mM | 0.1165 mL | 0.5825 mL | 1.1651 mL | 2.9126 mL | |
| 40 mM | 0.0874 mL | 0.4369 mL | 0.8738 mL | 2.1845 mL | |
| 50 mM | 0.0699 mL | 0.3495 mL | 0.6990 mL | 1.7476 mL | |
| 60 mM | 0.0583 mL | 0.2913 mL | 0.5825 mL | 1.4563 mL | |
| 80 mM | 0.0437 mL | 0.2184 mL | 0.4369 mL | 1.0922 mL | |
| 100 mM | 0.0350 mL | 0.1748 mL | 0.3495 mL | 0.8738 mL |