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Cat. No.: HY-133169

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Topazolin

Topazolin is a flavone. Topazolin has weak fungi-toxic activity against Cladosporium herbarum AHU 9262.

For research use only. We do not sell to patients.

CAS No.: 109605-79-0
Formula: C₂₁H₂₀O₆
Molecular Weight:368.38

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Topazolin Chemical Structure

CAS No.: 109605-79-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Topazolin is a flavone. Topazolin has weak fungi-toxic activity against Cladosporium herbarum AHU 9262^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	23.1 μM Compound: 21	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTS assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTS assay	[PMID: 26841168]
HepG2	IC₅₀	10.8 μM Compound: 21	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTS assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTS assay	[PMID: 26841168]
MCF7	IC₅₀	7.3 μM Compound: 21	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTS assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTS assay	[PMID: 26841168]
SW480	IC₅₀	16.1 μM Compound: 21	Cytotoxicity against human SW480 cells assessed as reduction in cell viability after 24 hrs by MTS assay Cytotoxicity against human SW480 cells assessed as reduction in cell viability after 24 hrs by MTS assay	[PMID: 26841168]

Chemical Information

CAS No. 109605-79-0
Molecular Weight 368.38
Formula C₂₁H₂₀O₆
SMILES

O=C1C(OC)=C(C2=CC=C(O)C=C2)OC3=CC(O)=C(C/C=C(C)\C)C(O)=C13
Structure Classification
- Flavonoids
- Flavones
- Phenols
- Polyphenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tahara S, et al. New 3-Methoxyflavones in the Roots of Yellow Lupin (Lupinus luteus L. cv. Topaz). Journal of the Agricultural Chemical Society of Japan, 1987, 51(4):1039-1044.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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