Pyrimorph
Based on 1 Customer Validation
Pyrimorph is a fungicide with excellent antifungal activity against oomycetes.
For research use only. We do not sell to patients.
- Purity: 95.61%
- CAS No.: 868390-90-3
- Formula: C22H25ClN2O2
- Molecular Weight:384.90
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Anti-Infection Compound Library
HY-L002
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Antifungal Compound Library
HY-L048
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Heterocyclic Compound Library
HY-L138
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MCE Bioactive Compound Library
HY-L001V
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Pesticide Compound Library
HY-L183
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
Pyrimorph inhibits different stages in the life cycle of P.capsici: mycelial growth (EC50 = 1.84 μg/mL), sporangia formation (EC50 = 0.17 μg/mL), zoospore release (EC50 = 4.92 μg/mL), cystospore germination (EC50 = 0.09 μg/mL)[1].
Pyrimorph exhibits 40.95% inhibition of oxygen consumption of intact mycelia at 100 μg/mL[1].
Pyrimorph inhibits the synthesis of cell wall either directly or indirectly from ultrastructural transformation of cell wall thickening and disruption of vacuoles[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Zebrafish (Brachydanio rerio), with an average body weight and length of about 0.30±0.10 g and 3.00±0.50 cm, respectively[2]
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Dosage:0-28 mg/L
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Administration:Exposure, 0-192 h
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Result:Had low toxicity to zebrafish, with LC50 values ranging from 24.33 mg/L (24 h) to 19.79 mg/L (96 h). Accumulated in fish shortly.
Chemical Information
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CAS No. 868390-90-3
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Appearance Solid
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Molecular Weight 384.90
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Formula C22H25ClN2O2
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Color White to off-white
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SMILES
O=C(N1CCOCC1)/C=C(C2=CC(Cl)=NC=C2)\C3=CC=C(C(C)(C)C)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (324.76 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Xiaojing Yan, et al. Study of inhibitory effects and action mechanism of the novel fungicide pyrimorph against Phytophthora capsici. J Agric Food Chem. 2010 Mar 10;58(5):2720-5. [Content Brief]
[2]. Chunqing Zhao, et al. Acute toxicity and bioconcentration of pyrimorph in zebrafish, Brachydanio rerio. Pest Manag Sci. 2011 Sep;67(9):1178-83. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.5981 mL | 12.9904 mL | 25.9808 mL | 64.9519 mL |
| 5 mM | 0.5196 mL | 2.5981 mL | 5.1962 mL | 12.9904 mL | |
| 10 mM | 0.2598 mL | 1.2990 mL | 2.5981 mL | 6.4952 mL | |
| 15 mM | 0.1732 mL | 0.8660 mL | 1.7321 mL | 4.3301 mL | |
| 20 mM | 0.1299 mL | 0.6495 mL | 1.2990 mL | 3.2476 mL | |
| 25 mM | 0.1039 mL | 0.5196 mL | 1.0392 mL | 2.5981 mL | |
| 30 mM | 0.0866 mL | 0.4330 mL | 0.8660 mL | 2.1651 mL | |
| 40 mM | 0.0650 mL | 0.3248 mL | 0.6495 mL | 1.6238 mL | |
| 50 mM | 0.0520 mL | 0.2598 mL | 0.5196 mL | 1.2990 mL | |
| 60 mM | 0.0433 mL | 0.2165 mL | 0.4330 mL | 1.0825 mL | |
| 80 mM | 0.0325 mL | 0.1624 mL | 0.3248 mL | 0.8119 mL | |
| 100 mM | 0.0260 mL | 0.1299 mL | 0.2598 mL | 0.6495 mL |
Pyrimorph Related Classifications
HY-123155 Related Classifications
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