- Signaling Pathways
- Metabolic Enzyme/Protease
- Glycosidase
Glycosidase
Glycosidase
- [1]. Wang X, et al. Metabolites extracted from microorganisms as potential inhibitors of glycosidases (α-glucosidase and α-amylase): A review. Front Microbiol. 2022 Nov 17;13:1050869.
- [2]. Ohtsubo K, et al. Glycosylation in cellular mechanisms of health and disease. Cell. 2006 Sep 8;126(5):855-67. [Content Brief]
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Glycosidase Substrates
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Glycosidase Ligands
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Glycosidase Related Products (686)
Related Products (686)
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Antibodies (3)
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Ganoderic acid Y
0 ImagesGanoderic acid Y is a α-glucosidase inhibitor with an IC50 of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating. -
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4-Aminophenyl-β-D-galactopyranoside, 98%
0 ImagesSynonyms: 4-Aminophenyl-beta-D-galactopyranoside, 98%4-Aminophenyl-β-D-galactopyranoside, 98% is a highly efficient substrate for β-galactosidase. It is specifically hydrolyzed by this enzyme to release galactose and electroactive p-aminophenol. 4-Aminophenyl-β-D-galactopyranoside, 98% is widely used in colorimetric and electrochemical assays for detecting β-galactosidase activity and determining enzyme kinetics, such as in biosensing fields including cellular senescence, pathogen and contaminant detection. In addition, since β-galactosidase is often overexpressed in primary ovarian cancer, 4-Aminophenyl-β-D-galactopyranoside, 98% can also be applied to related research on primary ovarian cancer. -
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1-Deoxynojirimycin (Standard)
0 ImagesSynonyms: Duvoglustat (Standard)1-Deoxynojirimycin (Standard) is the analytical standard of 1-Deoxynojirimycin. This product is intended for research and analytical applications. 1-Deoxynojirimycin (Duvoglustat) is a potent and orally active α-glucosidase inhibitor. 1-Deoxynojirimycin suppresses postprandial blood glucose and is widely used for diabetes mellitus. 1-Deoxynojirimycin possesses antihyperglycemic, anti-obesity, and antiviral features. -
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IHVR-19029
0 ImagesCat. No.: HY-124662CAS No.: 1447464-73-4IHVR-19029 is a potent endoplasmic reticulum (ER) α-glucosidases I and II inhibitor, with an IC50 of 0.48 μM for ER a-glucosidase I. IHVR-19029 efficiently blocks the replication of several hemorrhagic fever viruses, such as Dengue virus (DENV), Ebola virus (EBOV) and Rift Valley fever virus. The combination of IHVR-19029 with Favipiravir (HY-14768) improves the antiviral efficacy. -
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N-Caffeoyl O-methyltyramine
0 ImagesN-Caffeoyl O-methyltyramine is a class of alkaloid isolated from Cuscuta reflexa with strong inhibitory activity against α-glucosidase (IC50 of 103.58 μM). -
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Gallacetophenone
0 ImagesGallacetophenone is an inhibitor of α-glucosidase with an IC50 value of 408.6 μM. When combined with 1-Deoxynojirimycin (HY-14860), Gallacetophenone exhibits synergistic inhibitory effects on mammalian α-glucosidase at high concentrations. Gallacetophenone can be used in the study of diseases such as type 2 diabetes. -
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Glycyrrhisoflavone
0 ImagesGlycyrrhisoflavone, an active prenylflavonoid, inhibits α-glucosidase. -
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Allyl α-D-galactopyranoside
0 ImagesAllyl α-D-galactopyranoside is an α-galactoside and acceptor/donor substrate for transgalactosylation reactions. Allyl α-D-galactopyranoside acts as an acceptor substrate in α-galactosidase-catalyzed transgalactosylation, and serves as a donor substrate to form longer α-galactosyl-containing oligosaccharides. Allyl α-D-galactopyranoside serves as a model compound for investigating the catalytic mechanism and substrate specificity of glycoside hydrolases and glycosyltransferases. -
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- trans-2-Methoxycinnamic acid
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- Endoglycosidase S2 (D184M mutant)
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Glucocerebrosidase-IN-1 hydrochloride
0 ImagesGlucocerebrosidase-IN-1 (compound 11a) hydrochloride is a potent and selective GCase (glucocerebrosidase) inhibitor, with an IC50 of 29.3 μM and a Ki of 18.5 μM. Glucocerebrosidase-IN-1 hydrochloride can be used for the research of Gaucher disease (GD) and Parkinson’s disease (PD). -
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- Isoamylase
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α1-3,6 Galactosidase, Xanthomonas manihotis
0 Imagesα1-3,6 Galactosidase, Xanthomonas manihotis is a highly specific exoglycosidase that catalyzes the hydrolysis of α1-3 and α1-6 linked galactose residues from oligosaccharides. -
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PNGase F (Immobilized, Microspin)
0 ImagesCat. No.: HY-P2929BCAS No.: 83534-39-8PNGase F (Immobilized, Microspin) is a resin in which PNGase F (peptide N-glycosidase F) is covalently coupled to agarose beads, and it is used to remove N-glycans from antibodies, fusion proteins and other N-glycosylated proteins. The enzyme is recombinantly expressed in Escherichia coli, with its sequence derived from Flavobacterium meningsepticum. -
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α1-3,4 Fucosidase, Bifidobacterium bifidum
0 ImagesCat. No.: HY-132177CCAS No.: 9037-65-4α1-3,4 Fucosidase, Bifidobacterium bifidum is a broad specificity exoglycosidase that catalyzes the hydrolysis of terminal, non-reducing α1-3 and α1-4 linked fucose residues from oligosaccharides and glycoproteins. -
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Glyoxalase I
0 ImagesGlyoxalase I (Glo-I) is a glycosidase and a methylglyoxal (MOG) detoxification enzyme. Glyoxalase I can be used for the research of inflammation and cancer. -
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α-1-2 Fucosidase, bifidobacterium longum
0 ImagesCat. No.: HY-132177ACAS No.: 9037-65-4α1-2 Fucosidase (EC 3.2.1.51) is a highly specific exoglycosidase that catalyzes the hydrolysis of linear α1-2 linked fucose residues from oligosaccharides. -
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(+)-Afzelechin
0 Images(+)-Afzelechin, isolated from rhizomes of Bergenia ligulata, is an alpha-glucosidase activity inhibitor with an ID50 (50% inhibition dose) value of 0.13 mM. (+)-Afzelechin can delay the absorption of carbohydrates in food to suppress postprandial hyperglycemia and hyperinsulinemia. -
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Ganoderol B
0 ImagesCat. No.: HY-N2223CAS No.: 104700-96-1Synonyms: GanodermadiolGanoderol B is a potent α-glucosidase inhibitor. Ganoderol B has high α-glucosidase inhibition with an IC50 of 48.5 μg/mL (119.8 μM). -
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Maltose monohydrate-d14
0 ImagesCat. No.: HY-N2024ASMaltose monohydrate-d14 is the deuterium labeled Maltose monohydrate. Maltose monohydrate is a disaccharide composed of two glucose molecules linked together. Maltose monohydrate is an endogenous metabolic product in plants, yeast, or bacteria, and it participates in carbon source storage and metabolism. Maltose monohydrate is a key core metabolite and main transport form in the temporary starch degradation, carbon output, and subsequent sucrose synthesis metabolism of the night chloroplast. In X. dendrorhous, maltose can act as a sugar donor and is converted into isomaltulose by α-glucosidase. Maltose monohydrate can act as a osmotic agent, supporting continuous capillary ultrafiltration and preventing severe metabolic disorders. -
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