2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. PGC-1α
  5. PGC-1α Activator

PGC-1α Activator

PGC-1α Activators (5):

Cat. No. Product Name Effect Purity
  • HY-17538
    ZLN005
    		Activator 99.94%
    ZLN005 is a potent activator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α).
  • HY-N0378
    D-Mannitol
    		Activator 99.93%
    D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells.
  • HY-N7439
    Mogroside VI B
    		Activator 98.97%
    Mogroside VI B, a cucurbitane glucoside, separated from the crude extract of Siraitia grosvenorii. Mogroside VI B shows effect on activating PGC-1α transcription.
  • HY-17538S
    ZLN005-d4
    		Activator 99.52%
    ZLN005-d4 is deuterium labeled ZLN005. ZLN005 is a potent activator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α)[1].
  • HY-N12011
    11-Oxoisomogroside V
    		Activator
    11-Oxoisomogroside V (compound 3) is a cucurbitacin isolated from the crude extract of Luo Han Guo. 11-Oxoisomogroside V activates the transcriptional activity of PGC-1α. In the luciferase experiment, the results showed that 10 μM and 20 μM 11-Oxoisomogroside V could increase the luciferase activity to 133.79% and 143.81%.