ZLN005-d4
Based on 1 Customer Validation
ZLN005-d4 is deuterium labeled ZLN005. ZLN005 is a potent activator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α).
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- Pureté: 99.52%
- CAS No.: 2410443-42-2
- Formule: C17H14D4N2
- Masse moléculaire:254.36
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2410443-42-2
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Unlabeled CAS 49671-76-3
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Appearance Solid
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Masse moléculaire 254.36
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Formule C17H14D4N2
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Color White to off-white
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SMILES
CC(C)(C1=CC=C(C=C1)C2=NC3=C([2H])C([2H])=C([2H])C([2H])=C3N2)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 22 mg/mL (86.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Zhang LN, et al. Novel small-molecule PGC-1α transcriptional regulator with beneficial effects on diabetic db/db mice. Diabetes. 2013 Apr;62(4):1297-307. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9314 mL | 19.6572 mL | 39.3144 mL | 98.2859 mL |
| 5 mM | 0.7863 mL | 3.9314 mL | 7.8629 mL | 19.6572 mL | |
| 10 mM | 0.3931 mL | 1.9657 mL | 3.9314 mL | 9.8286 mL | |
| 15 mM | 0.2621 mL | 1.3105 mL | 2.6210 mL | 6.5524 mL | |
| 20 mM | 0.1966 mL | 0.9829 mL | 1.9657 mL | 4.9143 mL | |
| 25 mM | 0.1573 mL | 0.7863 mL | 1.5726 mL | 3.9314 mL | |
| 30 mM | 0.1310 mL | 0.6552 mL | 1.3105 mL | 3.2762 mL | |
| 40 mM | 0.0983 mL | 0.4914 mL | 0.9829 mL | 2.4571 mL | |
| 50 mM | 0.0786 mL | 0.3931 mL | 0.7863 mL | 1.9657 mL | |
| 60 mM | 0.0655 mL | 0.3276 mL | 0.6552 mL | 1.6381 mL | |
| 80 mM | 0.0491 mL | 0.2457 mL | 0.4914 mL | 1.2286 mL |
ZLN005-d4 Related Classifications
HY-17538S Related Classifications
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