1. Signaling Pathways
  2. Anti-infection
  3. Antibiotic

Antibiotic

Antibiotic

Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-129123
    ML318
    99.26%
    ML318 is a biaryl nitrile inhibitor of PvdQ acylase with an IC50 of 20 nM by binding in the acyl-binding site. ML318 inhibits P. aeruginosa (PAO1) with an IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions.
    ML318
  • HY-100528AR
    Dianemycin (Standard)
    4-Methoxycinnamic acid (Standard) is the analytical standard of 4-Methoxycinnamic acid. This product is intended for research and analytical applications. 4-Methoxycinnamic acid is detected as natural phenylpropanoid in A. preissii.
    Dianemycin (Standard)
  • HY-108288R
    Sulbactam pivoxil (Standard)
    Sulbactam pivoxil (Standard) (Pivsulbactam (Standard)) is the analytical standard of Sulbactam pivoxil (HY-108288). This product is intended for research and analytical applications. Sulbactam pivoxil (Pivsulbactam) is a prodrug of Sulbactam (HY-B0334) with oral activity. Sulbactam is a β-lactamase inhibitor with antibacterial activity. Sulbactam pivoxil is better absorbed than Sulbactam and results in higher serum levels after oral administration.
    Sulbactam pivoxil (Standard)
  • HY-B0454S
    Miconazole-d5
    Miconazole-d5 is the deuterium labeled Miconazole. Miconazole (R18134) is an imidazole antifungal agent. Miconazole also has antibacterial effects.
    Miconazole-d<sub>5</sub>
  • HY-B0466BR
    Cloxacillin sodium (Standard)
    Cloxacillin (sodium) (Standard) is the analytical standard of Cloxacillin (sodium). This product is intended for research and analytical applications. Cloxacillin sodium is an orally active antibacterial agent and β-lactamase inhibitor with an IC50 of 0.04 μM. Cloxacillin sodium can suppress the S. aureus-induced inflammatory response by inhibiting the activation of MAPKs, NF-кB and NLRP3-related proteins.
    Cloxacillin sodium (Standard)
  • HY-160968
    4-Demethoxy-7,9-di-epi-daunorubicin
    4-Demethoxy-7,9-di-epi-daunorubicin, a derivative of Daunorubicin (HY-13062A), is an anthracycline antibiotics. 4-Demethoxy-7,9-di-epi-daunorubicin can bind to calf thymus DNA and forms a complex with the stacked DNA base pairs. 4-Demethoxy-7,9-di-epi-daunorubicin can inhibit prokaryotic nucleic acid polymerases, including E. coli DNA polymerase I and RNA polymerase. 4-Demethoxy-7,9-di-epi-daunorubicin can be used for researches of cancer and infection.
    4-Demethoxy-7,9-di-epi-daunorubicin
  • HY-14926A
    Levonadifloxacin arginine hydrate
    Levonadifloxacin (arginine) hydrate is a broad-spectrum anti-staphylococcal agent. Levonadifloxacin (arginine) hydrate shows antibacterial activity against Methicillin (HY-121544)-susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant S. aureus (MRSA) strains, with a reduction of which phagocytized in THP-1 monocytes.
    Levonadifloxacin arginine hydrate
  • HY-121136
    Chartreusin
    Chartreusin is an antibiotic that is active against certain Gram-positive organisms and mycobacteria. Chartreusin is also active against the Micrococcus fiyogenes v. aureus phage.
    Chartreusin
  • HY-W011117S
    Danofloxacin-d3
    Danofloxacin-d3 is deuterium labeled Danofloxacin. Danofloxacin is an orally active quinolone antibiotic. Danofloxacin targets bacterial DNA gyrase and inhibits bacterial DNA replication, transcription and growth. Danofloxacin can be used for various bacterial infections caused by Escherichia coli, Mycoplasma and other pathogens.
    Danofloxacin-d<sub>3</sub>
  • HY-B0502AS
    Enrofloxacin-d5 hydrochloride
    Enrofloxacin-d5 (hydrochloride) is deuterium labeled Enrofloxacin (monohydrochloride). Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis.
    Enrofloxacin-d<sub>5</sub> hydrochloride
  • HY-108138
    FCE-25199
    FCE-25199 is an orally active penem antibiotic. FCE-25199 has antibacterial activity against various Gram positive and Gram negative bacteria. FCE-25199 is commonly used in the study of bacterial infections.
    FCE-25199
  • HY-B1781A
    Sulfachloropyridazine sodium
    99.34%
    Sulfachloropyridazine (sodium) is a sulfonamide antibiotic that inhibits bacterial growth.
    Sulfachloropyridazine sodium
  • HY-146449
    PXYD4
    PXYD4 is a ribosomal protein S1 (RpsA) antagonist with Kds of 3.24 and 1.64 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA plays an important role in the trans-translation process of Mycobacterium Tuberculosis (Mtb).
    PXYD4
  • HY-16742R
    Gepotidacin (Standard)
    Gepotidacin (Standard) is the analytical standard of Gepotidacin. This product is intended for research and analytical applications. Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor.
    Gepotidacin (Standard)
  • HY-12485R
    TBA-354 (Standard)
    Polyphyllin VI (Standard) is the analytical standard of Polyphyllin VI. This product is intended for research and analytical applications. Polyphyllin VI, an active saponin, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis. Polyphyllin VI induces caspase-1-mediated pyroptosis via the induction of ROS/NF-κB/NLRP3/GSDMD signal axis in non-small cell lung cancer.
    TBA-354 (Standard)
  • HY-100568
    3-O-Demethylfortimicin A
    3-O-Demethylfortimicin A (A-49759) is an aminocyclitol antibiotic with antibacterial activity. 3-O-Demethylfortimicin A is particularly effective against Gram-negative pathogens and staphylococcus.
    3-O-Demethylfortimicin A
  • HY-100436R
    Cadazolid (Standard)
    Cadazolid (Standard) is the analytical standard of Cadazolid. This product is intended for research and analytical applications. Cadazolid (ACT-179811) is a new oxazolidinone antibiotic with potent activity against Clostridium difficile.
    Cadazolid (Standard)
  • HY-121610
    FR-202306
    FR-202306 is a compound with antibacterial and peptide deformylase inhibitory activities, isolated from microorganisms, which has an inhibitory effect on the peptide deformylase of Staphylococcus aureus and also has antibacterial activity.
    FR-202306
  • HY-10393R
    Eperezolid (Standard)
    Eperezolid (Standard) is an analytical standard for Eperezolid. This product is intended for research and analytical applications. Eperezolid (PNU-100592) is an oxazolidinone antibiotic with good in vitro inhibitory properties.
    Eperezolid (Standard)
  • HY-138247
    β-Lactamase-IN-2
    98.59%
    β-Lactamase-IN-2 is a beta-lactamase inhibitor, extracted from patent WO 2019075084 A1, compound 1. β-Lactamase-IN-2 has anti-microbial and anti-bacterial effects.
    β-Lactamase-IN-2

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