1. Signaling Pathways
  2. Anti-infection
  3. Antibiotic

Antibiotic

Antibiotic

Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-P5728
    Aurein 1.1
    Aurein 1.1 is an antibiotic peptide that can be found in the Australian Bell Frogs Litoria raniformis.
    Aurein 1.1
  • HY-B1128AR
    Cefamandole sodium (Standard)
    Cefamandole (sodium) (Standard) is the analytical standard of Cefamandole (sodium). This product is intended for research and analytical applications. Cefamandole (Cephamandole) sodium is a semi-synthetic second-generation cephalosporin antibiotic with broad-spectrum antimicrobial activity. Cefamandole sodium is resistant to hydrolysis by β-lactamases produced by some Gram-negative bacteria. Cefamandole sodium kills Gram-positive cocci and various Gram-negative bacilli mainly by inhibiting cell wall synthesis, but it is inactive against Pseudomonas, Proteus vulgaris and Providencia stuartii, and its efficacy is affected by inoculum size. The plasma elimination half-life of Cefamandole sodium in rats is only 0.4 h, it is mainly excreted in urine in biologically active form, and it hardly penetrates the non-inflamed blood-brain barrier. Cefamandole sodium is widely used in studies related to bacterial infections.
    Cefamandole sodium (Standard)
  • HY-N14410
    Clecarmycin C
    Clecarmycin C is an antitumor antibiotic. Clecarmycin C shows cytotoxicity and antitumor activity. Clecarmycin C shows antimicrobial activity.
    Clecarmycin C
  • HY-182477
    Siccayne
    Siccayne, found in the marine basidiomycete Halocyphina villosa and deuteromycete Helminthosporium siccans, is an antibiotic. Siccayne interferes with nucleotide incorporation into DNA and RNA, precursor transport enzymatic reactions, and essential macromolecule synthesis. Siccayne inhibits Gram-positive bacteria and some fungi. Siccayne can be used for research on infections caused by bacteria and fungi.
    Siccayne
  • HY-N14251
    Melithiazole K
    Melithiazol K is an antibiotic. Melithiazole K is a β-methoxyacrylate (MOA) inhibitor with strong anti-agent activity.
    Melithiazole K
  • HY-N15344
    Euryachin E
    Euryachin E is an antimicrobial and antiviral agent found in Eurya chinensis. It exhibits a MIC of 6.25 μg/mL against B. cereus and 0.78 μg/mL against S. aureus. Its IC50 against COVID-19 is 6.41 μM. Euryachin E can be utilized for research in the fields of infection and inflammation.
    Euryachin E
  • HY-N15063
    10-Hydroxyundeca-2,4,6,8-tetraynamide
    10-Hydroxyundeca-2,4,6, 8-tetraynamide is a polyacetylene antibiotic. 10-Hydroxyundeca-2,4,6,8-tetraynamide has anti-Gram-positive bacteria, negative bacteria, yeast, fungus activity and cytotoxicity.
    10-Hydroxyundeca-2,4,6,8-tetraynamide
  • HY-129548
    Prumycin
    Prumycin is an antifungal antibiotic with activity against cucumber powdery mildew. Prumycin significantly inhibited the disease, whereas other metabolites such as bacillomycin D and surfactin did not. Prumycin did not induce the expression of plant defense genes, indicating that its effects were not through plant defense responses. Observation of cucumber cotyledons treated with prumycin showed that it could inhibit spore germination of P. fusca.
    Prumycin
  • HY-N15090
    Milbemycin α10
    Milbemycin α10 is a macrolide antibiotic. Milbemycin α10 has insecticidal effects on agricultural harmful insects, pans, larvae, etc.
    Milbemycin α10
  • HY-B0518AR
    Naftifine hydrochloride (Standard)
    Naftifine (hydrochloride) (Standard) is the analytical standard of Naftifine (hydrochloride). This product is intended for research and analytical applications. Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition.
    Naftifine hydrochloride (Standard)
  • HY-123448
    CCG-120304
    CCG-120304 is a TonB system inhibitor and bacteriostatic agent. CCG-120304 inhibits TonB-dependent functions. CCG-120304 is applicable to research related to urinary tract infections.
    CCG-120304
  • HY-118029
    Saroaspidin A
    Saroaspidin A is an antibiotic, which can be isolated from Hypericum japonicum thunb.
    Saroaspidin A
  • HY-135842R
    Aspoxicillin (Standard)
    Aspoxicillin (Standard) is the analytical standard of Aspoxicillin. This product is intended for research and analytical applications. Aspoxicillin is a broad-spectrum antimicrobial agent against 68 isolates of Actinobacillus pleuropneumoniae with an MIC90 value of <= 0.05 μg/ml. Aspoxicillin has a long half-life in mouse serum of 55 minutes.
    Aspoxicillin (Standard)
  • HY-119879
    Binfloxacin
    Binfloxacin (CP-73049) is a fluoroquinolone antibiotic. Binfloxacin does not inhibit the metabolism of theophylline, so it is safer to be used in combination with theophylline and other drugs metabolized by P450 1A2. Binfloxacin can be used in studies of bacterial infections.
    Binfloxacin
  • HY-A0294S
    Ertapenem-d4
    Ertapenem-d4 (MK-0826-d4) is deuterium labeled Ertapenem. Ertapenem (MK-0826) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract.
    Ertapenem-d<sub>4</sub>
  • HY-113582
    Albothricin
    Albothricin is a potent streptothricin Antibiotic with antimicrobial activities.
    Albothricin
  • HY-124425R
    5′-Deoxythymidine (Standard)
    Veratric acid (Standard) is the analytical standard of Veratric acid. This product is intended for research and analytical applications. Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant and anti-inflammatory activities. Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation.
    5′-Deoxythymidine (Standard)
  • HY-19581R
    Baquiloprim (Standard)
    Baquiloprim (Standard) is the analytical standard of Baquiloprim. This product is intended for research and analytical applications. Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria.
    Baquiloprim (Standard)
  • HY-N19907
    Phomopsinone A
    Phomopsinone A is an Antifungal agent. Phomopsinone A is isolated from Phomopsis sp. Phomopsinone A exhibits activity against plant and crop pathogens Pyricularia oryzae, Septoria tritici and Botrytis cinerea. Phomopsinone A can be used in the research of plant/crop fungal diseases.
    Phomopsinone A
  • HY-118051
    LY 186826
    LY 186826 is a γ-lactam antibiotic containing an aminothioazole methoxyacetic acid side chain at the C-7 position. LY186826 exhibits potent antibacterial activity against a wide range of Gram-positive and Gram-negative bacteria. LY186826 is inactivated by β-lactamases and Enterobacterases, showing stronger activity against Enterobacter strains.
    LY 186826

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