1. Signaling Pathways
  2. Anti-infection
  3. Antibiotic

Antibiotic

Antibiotic

Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-129814
    MM 42842 free acid
    MM 42842 free acid is a member of the monobactam family of β-lactam antibiotics.
    MM 42842 free acid
  • HY-N14138
    Diolmycin A1
    Diolmycin A1 is an antibiotic with anticoccidial activity.
    Diolmycin A1
  • HY-B0958R
    Mupirocin (Standard)
    Mupirocin (Standard) is the analytical standard of Mupirocin (HY-B0958). This product is intended for research and analytical applications. Mupirocin is an antibiotic. Mupirocin inhibits bacterial isoleucyl-tRNA synthetase, blocking protein synthesis. Mupirocin has high activity against Gram-positive bacteria such as Staphylococcus and Streptococcus, as well as some Gram-negative bacteria (such as Haemophilus influenzae). Mupirocin can be used in the research of diseases such as skin infections (such as MRSA infections) and chronic sinusitis.
    Mupirocin (Standard)
  • HY-B1174R
    Bekanamycin (Standard)
    Bekanamycin (Standard) is the analytical standard of Bekanamycin. This product is intended for research and analytical applications. Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain.
    Bekanamycin (Standard)
  • HY-117837
    GSK1829820A
    GSK1829820A has antitubercular activity which can inhibit Mycobacterium tuberculosis H37Rv.
    GSK1829820A
  • HY-N11407
    Bagougeramine B
    Bagougeramine B is an orally active nucleoside antibiotic with antimicrobial activity, which is found in Bacillus circulans. Bagougeramine B inhibits the growth of Gram-positive and Gram-negative bacteria and some fungi.
    Bagougeramine B
  • HY-23120
    1-Hydroxyguanidine sulfate
    1-Hydroxyguanidine sulfate is an antitumor agent that inhibits mast cell P815, leukaemia P388, leukaemia L1210 and carcinosarcoma Walker 256 cells growth. 1-Hydroxyguanidine sulfate also has antiviral activity.
    1-Hydroxyguanidine sulfate
  • HY-N14845
    Napsamycin A
    Napsamycin A is an antibiotic. Napsamycin A has antibacterial activity against Pseudomonas aeruginosa and other pseudomonas, but has weak antibacterial activity against other Gram-positive and negative bacteria.
    Napsamycin A
  • HY-B1894R
    Cefetamet pivoxyl (Standard)
    Cefetamet pivoxyl (Standard) is the analytical standard of Cefetamet pivoxyl. This product is intended for research and analytical applications. Cefetamet pivoxyl is a cephalosporin antibiotic. Cefetamet pivoxyl inhibits 355 enteropathogens Keime, Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila.
    Cefetamet pivoxyl (Standard)
  • HY-126577
    Dactylocycline B
    Dactylocycline B, an antibiotic, is active against gram-positive bacteria, including tetracycline-resistant bacteria.
    Dactylocycline B
  • HY-112542R
    Nemadectin (Standard)
    Nemadectin (Standard) is the analytical standard of Nemadectin. This product is intended for research and analytical applications. Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity.
    Nemadectin (Standard)
  • HY-N14233
    Inosamycin A
    Inosamycin A is a broad-spectrum antimicrobial antibiotic.
    Inosamycin A
  • HY-N13895
    Auramycin B
    Auramycin B, an anthracycline antibiotic that shows marked antibacterial activity against Gram-positive bacteria. Auramycin B also exhibits antitumor activity against P388 and L1210 leukemia in mice.
    Auramycin B
  • HY-169810
    PKZ18
    PKZ18 is an antibiotic and inhibits bacterial growth, with MIC values of 32-64 μg/mL against most Gram-positive bacteria. PKZ18 inhibits in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria and directly reduces T-box transcriptional read-through of the associated genes. PKZ18 prevents the codon-anticodon reading required for tRNA binding and is refractory to resistance.
    PKZ18
  • HY-159899
    DHFR-IN-22
    DHFR-IN-22 (Compound 8) is a DHFR (Dihydrofolate Reductase) inhibitor belonging to the class of 2,4-diaminopyrimidine compounds. DHFR-IN-22 exhibits significant inhibitory activity against purified DHFR enzyme and major species of nontuberculous mycobacteria (NTM), namely Mycobacterium avium and Mycobacterium abscessus. It shows an IC50 of 1.1 nM and MIC of 1.5 μg/mL against M. abscessus, and an IC50 of 6.3 nM and MIC of 0.1 μg/mL against M. avium. Additionally, it demonstrates an IC50 of 2100 nM against human DHFR. DHFR-IN-22 holds potential for studying novel strategies to combat NTM infections.
    DHFR-IN-22
  • HY-B1894AR
    Cefetamet pivoxil hydrochloride (Standard)
    Cefetamet pivoxil (hydrochloride) (Standard) is the analytical standard for Cefetamet pivoxil (hydrochloride). This product is intended for research and analytical applications. Cefetamet pivoxil hydrochloride is an oral third generation cephalosporin antibiotic.
    Cefetamet pivoxil hydrochloride (Standard)
  • HY-N14969
    Granaticin methyl ester
    Granaticin methyl ester is a quinone antibiotic. Granaticin methyl ester has anti-Gram positive bacteria and negative bacteria activity.
    Granaticin methyl ester
  • HY-N15068
    1-Hydroxyoxaunomycin
    1-Hydroxyoxaunomycin is an antibiotic. 1-Hydroxyoxaunomycin inhibits U210 cell growth, DNA synthesis and RNA synthesis with IC50 of 0.0005 μg/mL, 1.00 μg/mL and 0.76 μg/mL respectively.
    1-Hydroxyoxaunomycin
  • HY-B0946R
    Sulfamonomethoxine (Standard)
    Sulfamonomethoxine (Standard) is the analytical standard of Sulfamonomethoxine (HY-B0946). This product is intended for research and analytical applications. Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity.
    Sulfamonomethoxine (Standard)
  • HY-N6670R
    Cefotetan (Standard)
    Cefotetan (Standard) is the analytical standard of Cefotetan. This product is intended for research and analytical applications. Cefotetan is a semisynthetic cephamycin antibiotic that exerts its bactericidal effects by inhibition of cell-wall synthesis.
    Cefotetan (Standard)

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