2. Anti-infection
  3. Antibiotic Virus Protease
  4. 1-Hydroxyguanidine sulfate

1-Hydroxyguanidine sulfate is an antitumor agent that inhibits mast cell P815, leukaemia P388, leukaemia L1210 and carcinosarcoma Walker 256 cells growth. 1-Hydroxyguanidine sulfate also has antiviral activity.

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1-Hydroxyguanidine sulfate

1-Hydroxyguanidine sulfate Chemical Structure

CAS No. : 6345-29-5

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1-Hydroxyguanidine sulfate Related Antibodies

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Description

1-Hydroxyguanidine sulfate is an antitumor agent that inhibits mast cell P815, leukaemia P388, leukaemia L1210 and carcinosarcoma Walker 256 cells growth. 1-Hydroxyguanidine sulfate also has antiviral activity[1].

Molecular Weight

248.22

Formula

C2H12N6O6S
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

NC(NO)=N.O=S(O)(O)=O.NC(NO)=N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (402.87 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0287 mL 20.1434 mL 40.2868 mL
5 mM 0.8057 mL 4.0287 mL 8.0574 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.0287 mL 20.1434 mL 40.2868 mL 100.7171 mL
5 mM 0.8057 mL 4.0287 mL 8.0574 mL 20.1434 mL
10 mM 0.4029 mL 2.0143 mL 4.0287 mL 10.0717 mL
15 mM 0.2686 mL 1.3429 mL 2.6858 mL 6.7145 mL
20 mM 0.2014 mL 1.0072 mL 2.0143 mL 5.0359 mL
25 mM 0.1611 mL 0.8057 mL 1.6115 mL 4.0287 mL
30 mM 0.1343 mL 0.6714 mL 1.3429 mL 3.3572 mL
40 mM 0.1007 mL 0.5036 mL 1.0072 mL 2.5179 mL
50 mM 0.0806 mL 0.4029 mL 0.8057 mL 2.0143 mL
60 mM 0.0671 mL 0.3357 mL 0.6714 mL 1.6786 mL
80 mM 0.0504 mL 0.2518 mL 0.5036 mL 1.2590 mL
100 mM 0.0403 mL 0.2014 mL 0.4029 mL 1.0072 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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1-Hydroxyguanidine sulfate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1-Hydroxyguanidine6345-29-5AntibioticVirus Proteaseantitumour activityM-MSVLeukaemiaantiviralInhibitorinhibitorinhibit

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