1-Hydroxyguanidine sulfate
1-Hydroxyguanidine sulfate is an antitumor agent that inhibits mast cell P815, leukaemia P388, leukaemia L1210 and carcinosarcoma Walker 256 cells growth. 1-Hydroxyguanidine sulfate also has antiviral activity.
For research use only. We do not sell to patients.
- Purity : 95.0%
- CAS No.: 6345-29-5
- Formula: C2H12N6O6S
- Molecular Weight:248.22
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
Chemical Information
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CAS No. 6345-29-5
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Appearance Solid
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Molecular Weight 248.22
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Formula C2H12N6O6S
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Color White to light yellow
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SMILES
NC(NO)=N.O=S(O)(O)=O.NC(NO)=N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
H2O : ≥ 100 mg/mL (402.87 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.0287 mL | 20.1434 mL | 40.2868 mL | 100.7171 mL |
| 5 mM | 0.8057 mL | 4.0287 mL | 8.0574 mL | 20.1434 mL | |
| 10 mM | 0.4029 mL | 2.0143 mL | 4.0287 mL | 10.0717 mL | |
| 15 mM | 0.2686 mL | 1.3429 mL | 2.6858 mL | 6.7145 mL | |
| 20 mM | 0.2014 mL | 1.0072 mL | 2.0143 mL | 5.0359 mL | |
| 25 mM | 0.1611 mL | 0.8057 mL | 1.6115 mL | 4.0287 mL | |
| 30 mM | 0.1343 mL | 0.6714 mL | 1.3429 mL | 3.3572 mL | |
| 40 mM | 0.1007 mL | 0.5036 mL | 1.0072 mL | 2.5179 mL | |
| 50 mM | 0.0806 mL | 0.4029 mL | 0.8057 mL | 2.0143 mL | |
| 60 mM | 0.0671 mL | 0.3357 mL | 0.6714 mL | 1.6786 mL | |
| 80 mM | 0.0504 mL | 0.2518 mL | 0.5036 mL | 1.2590 mL | |
| 100 mM | 0.0403 mL | 0.2014 mL | 0.4029 mL | 1.0072 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
1-Hydroxyguanidine sulfate Related Classifications
HY-23120 Related Classifications
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