2. Signaling Pathways
  3. Anti-infection
  4. Antibiotic

Antibiotic

Antibiotic

Antibiotic

Related Products

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Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Antibiotic Isoform Specific Products:

Antibiotic Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-17580S1
    Fidaxomicin-d6
    Fidaxomicin-d6 (OPT-80-d6) is the deuterium labeled Fidaxomicin (HY-17580). Fidaxomicin (OPT-80), a macrocyclic antibiotic, is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti-Clostridium difficile activity (MIC90=0.12 μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research.
    Fidaxomicin-d<sub>6</sub>
  • HY-146970
    Lankacyclinone C
    Lankacyclinone C is a lankacidin C congener lacking the δ-lactone moiety, with antitumor activity.
    Lankacyclinone C
  • HY-P11098
    Peptide HV2
    Peptide HV2 is an antibiotic that exerts anti-inflammatory effects by inhibiting TNF-α. Peptide HV2 has antibacterial activity.
    Peptide HV2
  • HY-B1864AR
    Kasugamycin hydrochloride (Standard)
    Kasugamycin (Ksg) hydrochloride (Standard) is the analytical standard of Kasugamycin hydrochloride (HY-B1864A). This product is intended for research and analytical applications. Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes but not to the 50s subunit, and has anti-infective activity. Kasugamycin hydrochloride hydrate mimics mRNA nucleotides, disrupts tRNA binding and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate increases the sensitivity of mycobacteria to Rifampicin (HY-B0272) in vitro and in mouse infection models.
    Kasugamycin hydrochloride (Standard)
  • HY-A0294AS
    Ertapenem-d4 disodium
    Ertapenem-d4 (disodium) is deuterium labeled Ertapenem (disodium).
    Ertapenem-d<sub>4</sub> disodium
  • HY-14956S4
    Nemonoxacin-13C,d3 dihydrochloride
    Nemonoxacin-13C,d3 dihydrochloride (TG-873870-13C,d3 dihydrochloride) is the deuterium and 13C-labeled Nemonoxacin dihydrochloride. Nemonoxacin (TG-873870) is an orally active and potent broad-spectrum antibiotic. Nemonoxacin shows good inhibitory activity against different species of staphylococci, streptococci, and enterococci, Neisseria gonorrhoeae, and Haemophilus influenza. Nemonoxacin can be used in the study of bacterial infections and community-acquired pneumonia.
    Nemonoxacin-<sup>13</sup>C,d<sub>3</sub> dihydrochloride
  • HY-114749
    LL-C 10037α
    LL-C 10037α is an antitumor antibiotic and can be isolated from Streptomyces.
    LL-C 10037α
  • HY-146327
    PqsR/LasR-IN-1
    		98.13%
    PqsR/LasR-IN-1 (compound 2a) is a potent PqsR and LasR systems inhibitor. PqsR/LasR-IN-1 has anti-virulence activity against Pseudomonas aeruginosa. PqsR/LasR-IN-1 can reduce production of biofilm, pyocyanin, and rhamnolipids in PA.
    PqsR/LasR-IN-1
  • HY-B0925AS
    Oxacillin-d5
    Oxacillin-d5 is the deuterium labeled Oxacillin. Oxacillin is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens.
    Oxacillin-d<sub>5</sub>
  • HY-P5989
    Calpain inhibitor V
    Calpain inhibitor V (Mu-Val-HPh-FMK) is a cell-permeable and irreversible inhibitor of calpain that has anti-chlamydial activity.
    Calpain inhibitor V
  • HY-108357R
    6-Diazo-5-oxo-L-nor-Leucine (Standard)
    6-Diazo-5-oxo-L-nor-Leucine (Standard) is the analytical standard of 6-Diazo-5-oxo-L-nor-Leucine. This product is intended for research and analytical applications. 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[1][2][3].
    6-Diazo-5-oxo-L-nor-Leucine (Standard)
  • HY-N6728S
    Helvolic acid-13C33
    Helvolic acid-13C33 (Fumigacin-13C33) is the 13C-labeled Helvolic acid (HY-N6728). Helvolic acid (Fumigacin) is an antibiotic isolated from Xylaria sp, active against the Gram-positive bacteria.
    Helvolic acid-<sup>13</sup>C<sub>33</sub>
  • HY-P4128
    LL-37 SKE
    LL-37 SKE is an active fragment of LL-37.
    LL-37 SKE
  • HY-10197R
    Wortmannin (Standard)
    Wortmannin (Standard) is the analytical standard of Wortmannin. This product is intended for research and analytical applications. Wortmannin (SL-2052; KY-12420) is a potent, selective and irreversible PI3K inhibitor with an IC50 of 3 nM. Wortmannin also blocks autophagy formation, and potently inhibits Polo-like kinase 1 (PlK1) and Plk3 with IC50s of 5.8 and 48 nM, respectively.
    Wortmannin (Standard)
  • HY-158283
    Ethambutol-BSA
    Ethambutol-BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Ethambutol-BSA
  • HY-119261
    Ruboxyl
    Ruboxyl is an anthracycline antibiotic with antitumor activity. Ruboxyl inhibits colorectal cancer (CRC) liver metastasis in mice by 84%, suppresses B16 melanoma growth, and increases the survival rate of mice with L1210 or L5178Y leukemia.
    Ruboxyl
  • HY-137936
    Terrecyclic Acid
    Terrecyclic acid is a sesquiterpene originally isolated from A. terreus with antibiotic and anticancer activity. It is active against S. aureus, B. subtilis, and M. roseus (MICs=25, 50, and 25 μg/mL, respectively). Terrecyclic acid induces a heat shock response, increases levels of reactive oxygen species (ROS), and inhibits NF-κB activity and cell growth in 3T3-Y9-B12 cells.2 In vivo, terrecyclic acid (0.1, 1, and 10 mg/ml) reduces the number of ascitic fluid tumor cells in a mouse model of P388 murine leukemia.
    Terrecyclic Acid
  • HY-B1075AS
    (Rac)-Fosfomycin (benzylamine)-13C3
    (Rac)-Fosfomycin (benzylamine)-13C3 is the 13C labeled Fosfomycin. Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria.
    (Rac)-Fosfomycin (benzylamine)-<sup>13</sup>C<sub>3</sub>
  • HY-129356
    Seco-Duocarmycin SA
    Seco-Duocarmycin SA is a DNA alkylator. Seco-Duocarmycin SA is an antitumor antibiotic (IC50 = 10 pM). Seco-Duocarmycin SA can induce a concentration-dependent increase in apoptotic cell death. Seco-Duocarmycin SA can lead to significant cell cycle arrest in S and G2/M phases. Seco-Duocarmycin SA acts as an ADC cytotoxin for antibody-drug conjugates.
    Seco-Duocarmycin SA
  • HY-136443R
    4-Epitetracycline hydrochloride (Standard)
    4-Epitetracycline (hydrochloride) (Standard) is the analytical standard of 4-Epitetracycline (hydrochloride). This product is intended for research and analytical applications. 4-Epitetracycline hydrochloride is a reversible epimer of Tetracycline (HY-A0107) that can be interconverted in nature. 4-Epitetracycline hydrochloride exhibits antibacterial activity.
    4-Epitetracycline hydrochloride (Standard)
Antibiotic Isoform Comparison

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