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  4. Drug Isomer

Drug Isomer

Drug Isomer

Drug isomers are compounds with the same molecular formula but different atomic arrangements or spatial configurations. They are divided into structural isomers and stereoisomers, and have different biological activities, safety and metabolic characteristics. Drug isomers can be used as drug improvement groups or drug efficacy control groups. For example, Carvedilol has higher bioavailability and better safety than (R)-Carvedilol.

Drug Isomer Related Products (430):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-Z0031
    (R)-(-)-1,2-Propanediol
    		99.96%
    (R)-(-)-1,2-Propanediol is the (R)-isomer of 1,2-Propanediol (HY-Y0921). 1,2-Propanediol is an important bulk chemical product.
    (R)-(-)-1,2-Propanediol
  • HY-W587978
    12β-Hydroxyisocholic acid
    		99.66%
    12β-Hydroxyisocholic acid (Lagocholic acid) is a bile acid isomer that can be used in the study of bile acid metabolism.
    12β-Hydroxyisocholic acid
  • HY-D1306
    TAMRA azide, 6-isomer
    TAMRA azide, 6-isomer is an isomer of TAMRA. TAMRA azide, 6-isomer is the linker of TAMRA.
    TAMRA azide, 6-isomer
  • HY-N0521
    (-)-Gallocatechin
    		Control 99.98%
    (-)-Gallocatechin, an epimer of (-)-Epigallocatechin (EGC) (HY-N0225), is contained in various tea products. (-)-Gallocatechin demonstrates antioxidant activity in vitro, including inhibition of LDL oxidation and DPPH radical scavenging.
    (-)-Gallocatechin
  • HY-W001941
    D-Cystine
    		98.0%
    D-Cystine is the D-enantiomer of L-Cystine. D-Cystine inhibits L-aspartate-β-semialdehyde dehydrogenase (ASADH) from Escherichia coli.
    D-Cystine
  • HY-Y1010
    Oxiran-2-ylmethanol
    		99.95%
    Oxiran-2-ylmethanol (Glycidol) is an ester product. Oxiran-2-ylmethanol induces base pair point mutations in bacterial strains and structural chromosome aberrations in cultured cells. Oxiran-2-ylmethanol forms N-(2,3-dihydroxypropyl)valine hemoglobin adducts. Oxiran-2-ylmethanol acts as an animal carcinogen but does not significantly induce micronucleated immature erythrocytes in animal bone marrow. Oxiran-2-ylmethanol enables anionic polymerization to produce linear poly(glycidol). Oxiran-2-ylmethanol can be used for cancer-related research.
    Oxiran-2-ylmethanol
  • HY-103019B
    (-)-Enitociclib
    		99.85%
    (-)-Enitociclib ((R)-Enitociclib) is an enantiomer of Enitociclib (HY-103019E) with an optical rotation of (-). Enitociclib is a selective CDK9 inhibitor and apoptosis inducer. Enitociclib inhibits CDK9 activity and reduces the phosphorylation of Ser2 in the carboxyl-terminal domain (CTD) of RNA polymerase Pol II, thereby downregulating the transcription of key oncogenes such as MYC and MCL1. Enitociclib has anti-proliferative activity targeting MYC+ lymphoma and multiple myeloma (MM) cells, and has synergistic effects with Bortezomib (HY-10227) and Lenalidomide (HY-A0003), and can be used in the research of hematological malignancies.
    (-)-Enitociclib
  • HY-N0654
    Corypalmine
    		99.51%
    Corypalmine is an alkaloid identified in the dried tubers of Corydalis Decumbens Pers, with an oral bioavailability of 4.6% in mice. Corypalmine exhibits poor gastrointestinal absorption properties, which correlate with its high hydrophilicity and low permeability.
    Corypalmine
  • HY-W041301
    (±)-Dihydroactinidiolide
    		99.96%
    (±)-Dihydroactinidiolide is the dextrorotatory form of Dihydroactinidiolide (HY-107805). (±)-Dihydroactinidiolide has a strong, pleasant musky, tea-like and tobacco-like aroma and is mainly found in black tea, tobacco and fruits. (±)-Dihydroactinidiolide has antioxidant activity and can be derived from β-carotene.or light adaptation in Arabidopsis.
    (±)-Dihydroactinidiolide
  • HY-126076
    VPC-80051 racemate
    		98.99%
    VPC-80051 racemate is a racemate of VPC-80051. VPC-80051 is a prototype inhibitor of the hnRNP A1 splicing factor.
    VPC-80051 racemate
  • HY-126066
    (-)-Syringaresinol
    		99.93%
    (-)-Syringaresinol is an orally active isomer of syringaresinol (HY-N8307) found in Annona Montana. (-)-Syringaresinol exhibits antioxidant, anti-inflammatory, and anticancer activities. (-)-Syringaresinol can alleviate ulcerative colitis via the PI3K-Akt/MAPK/Wnt signaling pathway. (-)-Syringaresinol inhibits HL-60 cell proliferation by arresting the G1 phase and inducing apoptosis. (-)-Syringaresinol inhibits LPS (HY-D1056)-induced microglial activation by downregulating the NF-κB p65 signaling pathway and its interaction with ERβ, exerting anti-neuroinflammatory effects.
    (-)-Syringaresinol
  • HY-W007880
    (R)-D2PM
    		99.93%
    (R)-D2PM ((R)-Diphenylprolinol) is an isomer of the psychoactive substance D2PM and a pyrrolidine analog.
    (R)-D2PM
  • HY-112066B
    (-)-SHIN1
    		99.37%
    (-)-SHIN1 ((-)-RZ-2994) is an inactive (−) enantiomer of SHIN1.
    (-)-SHIN1
  • HY-N6020
    (-)-Butin
    		99.57%
    (-)-Butin is a enantiomer of Butin (HY-N6020B). Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities.
    (-)-Butin
  • HY-101325
    (S,S)-BRL-37344 sodium
    		99.90%
    (S,S)-BRL-37344 sodium is an isomer of BRL-37344 (HY-101325B). BRL-37344 is a β-adrenoceptor agonist with EC50 values of 5.3, 18 and 570 nM for β3, β2 and β1. BRL-37344 induces concentration-dependent increases in atria1 rate, relaxation of guinea pig trachea and lipolysis of brown adipocytes.
    (S,S)-BRL-37344 sodium
  • HY-101325A
    (S,S)-BRL-37344
    		99.45%
    (S,S)-BRL-37344 is an isomer of BRL-37344 (HY-101325B). BRL-37344 is a β-adrenoceptor agonist with EC50 values of 5.3, 18 and 570 nM for β3, β2 and β1. BRL-37344 induces concentration-dependent increases in atria1 rate, relaxation of guinea pig trachea and lipolysis of brown adipocytes.
    (S,S)-BRL-37344
  • HY-100218C
    (1R,3R)-RSL3
    		Control 99.05%
    (1R,3R)-RSL3 is an isomer of RSL3 (HY-100218A). RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells.
    (1R,3R)-RSL3
  • HY-111664A
    (S)​-​(-​)​-​Citronellal
    		Chemical 99.66%
    (S)-(-)-Citronellal ((-​)​-​Citronellal) is an oxygenated monoterpenoid found in Citrus limon (L.) Burm. F. essential oils. (S)-(-)-Citronellal is a chiral isomers of (R)-(+)-Citronellal (HY-111664) and does not possess microtubule-disrupting activity. (S)-(-)-Citronellal can be used for cancer research.
    (S)​-​(-​)​-​Citronellal
  • HY-160440
    rel-VU6021625
    		99.67%
    rel-VU6021625 is the relative configuration of VU6021625 (HY-160440A). VU6021625 is a potent and selective mAChR M4 antagonist with IC50 values of 0.44 nM and 57 nM for human M4, rat M4, respectively.
    rel-VU6021625
  • HY-W007140
    2-Hydroxymethyl-5-hydroxypyridine
    		99.67%
    2-Hydroxymethyl-5-hydroxypyridine is isolated from the the matured, ripened and dried seeds of S. lychnophora.
    2-Hydroxymethyl-5-hydroxypyridine