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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W127820
    H2TMpyP-2 chloride
    		≥99.0%
    H2TMpyP-2 (tetrakis(2-N-methylpyridyl)porphine) chloride is an active photosensitizer with strong absorption properties in the visible to near-infrared region and excellent singlet oxygen quantum yield. Captisol-TMPyP complexes can be used in supramolecular nanosynthesis to increase singlet oxygen production, improve photostability and better photosensitization, and support photodynamic therapy activity. The Captisol:TMPyP complex also exhibited antibacterial activity against Escherichia coli and was cytotoxic against lung cancer A549 cells.
    H2TMpyP-2 chloride
  • HY-148073
    MeO-Succ-Arg-Pro-Tyr-AMC TFA
    		98.21%
    MeO-Succ-Arg-Pro-Tyr-AMC TFA is a fluorogenic peptide substrate for chymotrypsin-like proteases that detects protease activity. (measured at 460 nm)
    MeO-Succ-Arg-Pro-Tyr-AMC TFA
  • HY-DY1033
    C12FDG (solution)
    C12FDG (5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside) (solution) is a lipophilic green fluorescent substrate for β-galactosidase detection. C12-FDG is more sensitive than Fluorescein di (β-D-galactopyranoside) (HY-101895) for beta-galactosidase activity determinations in animal cells (Ex/Em = 488/523 nm) .
    Solvent and concentration: DMSO: 10 mM
    C12FDG (solution)
  • HY-D2841
    FITC-Heparin
    FITC-Heparin is a fluorescent dye composed of FITC (HY-66019) and Heparin. FITC-Heparin can be used for cell tracing and drug delivery.
    FITC-Heparin
  • HY-135637
    Nilotinib Acid
    Nilotinib Acid, an analogue of Nilotinib, is usually used as a labeled chemical or fluorescent probe.
    Nilotinib Acid
  • HY-D0165
    Naphthoresorcinol
    		99.60%
    Naphthoresorcinol (1,3-Dihydroxynaphthalene) is a fluorescent dye (λex=330 nm, λem=380 nm) that can react with the NPPD (a tracer) and concentrated HCl and develop a red color. Naphthoresorcinol could be used as a background electrolyte (BGE) to determine the carbohydrates.
    Naphthoresorcinol
  • HY-118924
    IR-825
    		98.27%
    IR-825 is a near infrared fluorescent dye.the end of IR-825 has carboxyl COOH active group, and can participate in the reaction to connect other molecules. IR-825 can be widely used in tumor photothermal study..
    IR-825
  • HY-D2923
    PA-JF549-Halo ligand
    		99.34%
    PA-JF549-Halo ligand is a covalently linked conjugate comprising the photoactivatable fluorescent dye PA-JF549 and a ligand for the HaloTag protein. PA-JF549-Halo ligand exhibts inherent structural properties and predispose it to localize within mitochondria. PA-JF549-Halo ligand combines the exceptional brightness, photostability, and cell permeability of the JF549 dye with photoactivation capabilities and the high specificity characteristic of HaloTag protein labeling technology. PA-JF549-Halo ligand enables high-quality single-molecule imaging and super-resolution imaging of specific proteins within live cells.
    PA-JF549-Halo ligand
  • HY-DY1016
    FITC-Dextran (MW 10000) (solution)
    FITC-Dextran (MW 10000) (solution) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 10000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 10000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption.
    Solvent and Concentration: Sterile water: 2 mM
    FITC-Dextran (MW 10000) (solution)
  • HY-129887
    Fluorescein diphosphate tetraammonium
    Fluorescein diphosphate tetraammonium is a fluorescent dye, it can be used as a fluorogenic substrate and generats fluorescein as a fluorescent product.
    Fluorescein diphosphate tetraammonium
  • HY-D0134
    NIR-797-isothiocyanate
    		99.26%
    NIR-797-isothiocyanate is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    NIR-797-isothiocyanate
  • HY-126220
    KMG-301AM
    KMG-301AM is the acetoxy methyl esterified form of KMG-301. KMG-301AM successfully accumulates in mitochondria and then it is hydrolyzed to KMG-301. KMG-301 is an Mg2+-selective fluorescent probe functional in mitochondria in intact cells. Since the mitochondrial membrane is impermeable to KMG-301, it is not released upon depolarization of the mitochondrial membrane potential. KMG-301 can indicate changes in mitochondrial Mg2+ concentration and shows Mg2+ transport across the mitochondrial membrane in the early phases of a cellular model.
    KMG-301AM
  • HY-D0164
    Naphthol AS-BI
    		99.86%
    Naphthol AS-BI is a substrate of β-glucuronidase and produces a bright red effect after staining biological tissues.
    Naphthol AS-BI
  • HY-D0324
    Pigment Yellow 101
    		98.06%
    Pigment Yellow 101 is a yellow bis-azomethine pigment (excitation/emission: 411 nm/512 nm). Pigment Yellow 101 exhibits solid-state fluorescence. Pigment Yellow 101 is available as a commercial colorant.
    Pigment Yellow 101
  • HY-P1859
    MCA-SEVNLDAEFR-K(Dnp)-RR, amide
    		98.38%
    MCA-SEVNLDAEFR-K(Dnp)-RR, amide is a FRET-based substrate.
    MCA-SEVNLDAEFR-K(Dnp)-RR, amide
  • HY-D1359
    Mito Red
    Mito Red is a vital dye and mitochondrial stain that can be used to detect and evaluate mitochondrial function and status. Mito Red accumulates in mitochondria, and its fluorescence intensity is positively correlated with mitochondrial membrane potential. When the mitochondrial membrane potential increases, the fluorescence signal of Mito Red increases.
    Mito Red
  • HY-126367
    Light green SF yellowish
    Light green SF yellowish (Acid Green 5) is a water-soluble triarylmethane dye. Light green SF yellowish serves as a histological stain that selectively labels mitochondria, collagen, and cartilage, while being an essential component of Papanicolaou staining. Light green SF yellowish is commonly used as a cytoplasmic counterstain for nuclear stains, and is applied in Masson's trichrome staining for collagen fibers, Pap staining, and cytological polychromatic staining in histopathology. Light green SF yellowish also induces growth inhibition and local fibrosarcomas in rats and exerts mild pulmonary tumorigenicity in mice.
    Light green SF yellowish
  • HY-D1325
    Cyanine5.5 alkyne chloride
    		99.00%
    Cyanine5.5 alkyne chloride is an alkynyl-modified near-infrared (NIR) fluorescent dye (Ex=678 nm, Em=694 nm). Cyanine5.5 alkyne chloride can react with azides for click chemistry labeling.
    Cyanine5.5 alkyne chloride
  • HY-B1273
    Fenipentol
    		98.28%
    Fenipentol (1-Phenyl-1-pentanol), a synthetic derivative of an ingredient of Curcuma longa that is used as a condiment and dye. Fenipentol is also an orally active choleretic agent that plays an important role in release of secretin, gastrin, and pancreatic secretion of bicarbonate and protein.
    Fenipentol
  • HY-W440911
    DSPE-PEG2000-Cy5
    		99.91%
    DSPE-PEG2000-Cy5 is a Cy5 (HY-D0821) fluorophore-labeled conjugate of distearoylphosphatidylethanolamine and polyethylene glycol, as well as a liposome component. The Cy5 fluorophore is commonly used for labeling proteins and nucleic acids in imaging, flow cytometry and genomic applications. DSPE-PEG2000-Cy5 supports cell membrane modification, in vivo tumor targeting research and long-term in vivo circulation of its liposomal formulations (Ex/Em=633/670 nm).
    DSPE-PEG2000-Cy5
Cat. No. Product Name / Synonyms Application Reactivity