PA-JF549-Halo ligand

Cat. No.: HY-D2923 Purity: 99.34%: Data Sheet
COA

SDS
Handling Instructions
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PA-JF549-Halo ligand is a covalently linked conjugate comprising the photoactivatable fluorescent dye PA-JF549 and a ligand for the HaloTag protein. PA-JF549-Halo ligand exhibts inherent structural properties and predispose it to localize within mitochondria. PA-JF549-Halo ligand combines the exceptional brightness, photostability, and cell permeability of the JF549 dye with photoactivation capabilities and the high specificity characteristic of HaloTag protein labeling technology. PA-JF549-Halo ligand enables high-quality single-molecule imaging and super-resolution imaging of specific proteins within live cells.

For research use only. We do not sell to patients.

PA-JF549-Halo ligand Chemical Structure

CAS No. : 1811539-43-1

Size	Stock	Quantity
100 μg	In-stock	Estimated Time of Arrival: December 31
500 μg	In-stock	Estimated Time of Arrival: December 31
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

684.22

Formula

C₃₈H₄₂ClN₅O₅

CAS No.

1811539-43-1

Appearance

Solid

Color

Light yellow to yellow

SMILES

ClCCCCCCOCCOCCNC(C1=CC=C(C2=O)C(C3(C2=[N+]=[N-])C4=CC=C(C=C4OC5=CC(N6CCC6)=CC=C53)N7CCC7)=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (73.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.4615 mL	7.3076 mL	14.6152 mL
5 mM	0.2923 mL	1.4615 mL	2.9230 mL
10 mM	0.1462 mL	0.7308 mL	1.4615 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.34%

Select Batch:

Data Sheet (270 KB) SDS (251 KB)

COA (248 KB) HNMR (392 KB) RP-HPLC (257 KB) LCMS (361 KB)

Handling Instructions (2659 KB)

References

[1]. Grimm JB, et al. Bright photoactivatable fluorophores for single-molecule imaging. Nat Methods. 2016 Dec;13(12):985-988. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.4615 mL	7.3076 mL	14.6152 mL	36.5380 mL
	5 mM	0.2923 mL	1.4615 mL	2.9230 mL	7.3076 mL
	10 mM	0.1462 mL	0.7308 mL	1.4615 mL	3.6538 mL
	15 mM	0.0974 mL	0.4872 mL	0.9743 mL	2.4359 mL
	20 mM	0.0731 mL	0.3654 mL	0.7308 mL	1.8269 mL
	25 mM	0.0585 mL	0.2923 mL	0.5846 mL	1.4615 mL
	30 mM	0.0487 mL	0.2436 mL	0.4872 mL	1.2179 mL
	40 mM	0.0365 mL	0.1827 mL	0.3654 mL	0.9134 mL
	50 mM	0.0292 mL	0.1462 mL	0.2923 mL	0.7308 mL
	60 mM	0.0244 mL	0.1218 mL	0.2436 mL	0.6090 mL