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  4. Asterric Acid

Asterric Acid  (Synonyms: Dimethylosoic acid; RES-1214-1; TAN 1415A)

Cat. No.: HY-119843
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Asterric acid is an antibiotic fungal metabolite that completely inhibits the binding of the potent vasoconstrictor endothelin (ET)-1 to the ETA receptor in A10 cells at 0.1 μM.1 Asterric acid derivatives have also been shown to inhibit VEGF-induced tube formation of human umbilical vein endothelial cells at 3-10 μM, which suggests its usefulness as an antiangiogenic agent.

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Asterric Acid

Asterric Acid Chemical Structure

CAS No. : 577-64-0

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Asterric Acid Related Antibodies

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Description

Asterric acid is an antibiotic fungal metabolite that completely inhibits the binding of the potent vasoconstrictor endothelin (ET)-1 to the ETA receptor in A10 cells at 0.1 μM.1 Asterric acid derivatives have also been shown to inhibit VEGF-induced tube formation of human umbilical vein endothelial cells at 3-10 μM, which suggests its usefulness as an antiangiogenic agent.

Cellular Effect
Cell Line Type Value Description References
A10 IC50
1 × 10-5M
Compound: 3
Displacement of endothelin-1 from ETA receptor in rat A10 cells
Displacement of endothelin-1 from ETA receptor in rat A10 cells
[PMID: 11809055]
A10 IC50
1 x 10-5M
Compound: 3
Displacement of endothelin-1 from ETA receptor in rat A10 cells
Displacement of endothelin-1 from ETA receptor in rat A10 cells
[PMID: 11809055]
Masse moléculaire

348.30

Formule

C17H16O8
CAS No.
SMILES

CC1=CC(O)=C(C(OC2=C(C=C(C=C2C(OC)=O)O)OC)=C1)C(O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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Asterric Acid Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Asterric Acid577-64-0Dimethylosoic acid RES-1214-1 TAN 1415AAntibioticInhibitorinhibitorinhibit

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