1. GPCR/G Protein
  2. LPL Receptor
  3. CAY10444

CAY10444 (Synonyms: BML-241)

Cat. No.: HY-119401
Handling Instructions

CAY10444 (BML-241) is a sphingosine-1-phosphate 3 (S1P3) antagonist. CAY10444 inhibits by 37% S1P-induced increases in Ca2+ in HeLa cells expressing S1P3 receptors.

For research use only. We do not sell to patients.

CAY10444 Chemical Structure

CAY10444 Chemical Structure

CAS No. : 298186-80-8

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Description

CAY10444 (BML-241) is a sphingosine-1-phosphate 3 (S1P3) antagonist. CAY10444 inhibits by 37% S1P-induced increases in Ca2+ in HeLa cells expressing S1P3 receptors[1].

IC50 & Target[1]

S1PR3

 

In Vitro

BML-241 inhibits increases in intracellular Ca2+ concentration via P2 receptor or α1A-adrenoceptor stimulation and α1A-adrenoceptor-mediated contraction of rat mesenteric artery, while it does not affect S1P3-mediated decrease of Forskolin-induced cyclic AMP accumulation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

287.46

Formula

C15H29NO2S

CAS No.
SMILES

O=C(O)[[email protected]]1NC(SC1)CCCCCCCCCCC

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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CAY10444
Cat. No.:
HY-119401
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