2. Peptides

Peptides

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Peptides, which are short chains of amino acids linked by peptide bonds, have a variety of biological functions, such as, anti-thrombosis, anti-hypertension, anti-microbial, anti-tumor and anti-oxidation, immune-regulation, and cholesterol-lowering effects. Peptides have been widely used in functional analysis, antibody research, vaccine research, and especially the field of drug research and development.

MedChemExpress (MCE) offers a comprehensive collection of high quality peptides including peptide inhibitors, β-amyloids, therapeutic peptides and amino acid derivatives to clients in pharmaceutical and academic institutions all over the world. Unlimited Custom Peptide Service is also available to help researchers propel their projects.

Peptides

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Peptides (9394):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-106228
    HLF1-11 183623-03-2 99.73%
    HLF1-11, a human lactoferrin-derived peptide, is a broad spectrum antimicrobial agent. HLF1-11 inhibits human MPO activity. HLF1-11 also directs GM-CSF-driven monocyte differentiation toward macrophages, and enhances immune responses.
    HLF1-11
  • HY-118694
    TAPI-0 163958-73-4
    TAPI-0 is a TACE (TNF-α converting enzyme; ADAM17) inhibitor with an IC50 of 100 nM. TAPI-0 is a MMP inhibitor and also attenuates TNF-α processing.
    TAPI-0
  • HY-135108
    QWF Peptide 126088-82-2 98.51%
    QWF Peptide (Compound 4a) is a substance P antagonist with an IC50 of 0.09 μM. QWF Peptide antagonizes the SP-induced contraction of isolated guinea pig trachea strips with an IC50 of 4.7 μM.
    QWF Peptide
  • HY-P0226A
    TFLLR-NH2TFA 1313730-19-6 99.62%
    TFLLR-NH2 (TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM.
    TFLLR-NH2TFA
  • HY-P11072
    IRF5-CPP5 1601299-92-6 99.23%
    IRF5-CPP5 is a cytosolic peptide that selectively targeting human IRF5 wirh a Kd of 0.53 μM. IRF5-CPP5 disrupts IRF5 homodimerization and inhibits its nuclear translocation without altering IRF5 phosphorylation levels. IRF5-CPP5 inhibits proinflammatory cytokine (IL-6, IL-1β, TNF-α) production. IRF5-CPP5 can be used for the research of systemic lupus erythematosus.
    IRF5-CPP5
  • HY-P1339B
    Orexin B, human acetate 99.68%
    Orexin B, human acetate is the acetate form of Orexin B, human (HY-P1339). Orexin B, human acetate is the agonist for Orexin Receptor, with Ki of 420 nM and 36 nM for OX1 and OX2. Orexin B, human acetate participates in the regulation of appetite, wakefulness, cardiovascular function and neuroendocrine.
    Orexin B, human acetate
  • HY-P1832A
    PTD-p65-P1 Peptide TFA 99.92%
    PTD-p65-P1 Peptide TFA is a potent, selective nuclear transcription factor NF-κB inhibitor and derives from the p65 subunit of NF-κB amino acid residues 271-282, which selectively inhibits NF-κB activation induced by various inflammatory stimulation, down-regulate NF-κB-mediated gene expression and up-regulate apoptosis.
    PTD-p65-P1 Peptide TFA
  • HY-P2171A
    CCP peptide TFA
    CCP peptide TFA is a synthetic cyclic citrullinated peptide (CCP) and used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide TFA functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA).
    CCP peptide TFA
  • HY-P2333A
    LCKLSL hydrochloride 98.05%
    LCKLSL hydrochloride is a N-terminal hexapeptide and a competitive annexin A2 (AnxA2) inhibitor. LCKLSL hydrochloride potently inhibits the binding of tissue plasminogen activator (tPA) to AnxA2. LCKLSL hydrochloride also inhibits the generation of plasmin and has anti-angiogenic roles.
    LCKLSL hydrochloride
  • HY-P4744A
    LL-37 amide TFA 99.97%
    LL-37 amide TFA is a selective agonist of formyl peptide receptor-like FPRL1, effectively inhibiting periodontal pathogens (ED99=8.5-8.7 μg/mL). LL-37 amide TFA exerts its bactericidal effect by activating FPRL1-mediated immune cell chemotaxis and disrupting bacterial cell membrane integrity. It can also regulate inflammatory responses (inhibiting the release of factors such as TNF-α) and promote angiogenesis. Amidation modification reduces its sensitivity to serum inhibition and improves its stability. LL-37 amide TFA possesses key activities in bactericidal action, immunomodulation, and wound healing, and is mainly used in research on infection-related diseases such as periodontal disease and deep tissue injuries (pressure ulcers), and wound healing.
    LL-37 amide TFA
  • HY-P6365B
    APP-018 452782-06-8 99.80%
    APP-018 (D-4F) is 18 D-amino acids peptide that mimics apolipoprotein A-I (apoA-I). APP-018 improves the anti-inflammatory activity of high-density lipoprotein (HDL). APP-018 can be used in researches of cardiovascular diseases.
    APP-018
  • HY-129724A
    α-MSH (11-13) acetate 2828433-34-5 99.31%
    α-MSH (11-13) (ACTH-(11-13)) acetate is a C-terminal tripeptide of α-MSH that can cross the blood-brain barrier. α-MSH (11-13) acetate exhibits antipyretic, anti-inflammatory, and antibacterial activities. α-MSH (11-13) acetate also exerts neuroprotective effects after traumatic brain injury by inhibiting excessive activation of microglia and reducing neuronal apoptosis. α-MSH (11-13) acetate can be used in research related to traumatic brain injury, fever, and bacterial infections.
    α-MSH (11-13) acetate
  • HY-W007618
    Boc-Lys-OH 13734-28-6 ≥98.0%
    Boc-Lys-OH is an amino acid derivative. Boc-Lys-OH plays a key role in peptide synthesis and redox activity research.
    Boc-Lys-OH
  • HY-W008995
    Fmoc-Phe(4-F)-OH 169243-86-1
    Fmoc-Phe(4-F)-OH is a phenylalanine derivative.
    Fmoc-Phe(4-F)-OH
  • HY-W009177
    S-Methylglutathione 2922-56-7 99.40%
    S-Methylglutathione is an S-substitued glutathione and a stronger nucleophile than GSH. S-Methylglutathione has inhibitory effect on glyoxalase 1.
    S-Methylglutathione
  • HY-W010959
    Fmoc-Asp-OtBu 129460-09-9 ≥98.0%
    Fmoc-Asp-OtBu is an aspartic acid derivative.
    Fmoc-Asp-OtBu
  • HY-W011342
    Fmoc-Sar-OH 77128-70-2 99.93%
    Fmoc-Sar-OH is a Glycine (HY-Y0966) derivative.
    Fmoc-Sar-OH
  • HY-P0076
    TAK-448 1234319-68-6 99.90%
    TAK-448 (MVT-602) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM.
    TAK-448
  • HY-P2244
    YAP-TEAD-IN-1 1659305-78-8 99.68%
    YAP-TEAD-IN-1 is a potent and competitive inhibitor of?YAP–TEAD interaction (IC50=25 nM). YAP-TEAD-IN-1 is a 17mer peptide and shows a higher the binding affinity to TEAD1 (Kd=15 nM) than YAP (50-171) (Kd=40 nM).
    YAP-TEAD-IN-1
  • HY-125586
    β-Amanitin 21150-22-1
    β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs).
    β-Amanitin