2. Metabolic Enzyme/Protease Neuronal Signaling Stem Cell/Wnt MAPK/ERK Pathway
  3. Endogenous Metabolite Amyloid-β ERK
  4. Pyridoxal Phosphate-d3

Pyridoxal Phosphate-d3  (Synonyms: Pyridoxal 5'-phosphate-d3)

Cat. No.: HY-W011727S Pureza: 98.01%
COA
SDS
Instrucciones de manejo Technical Support

Pyridoxal Phosphate-d3 is the deuterium labeled Pyridoxal 5'-phosphate. Pyridoxal 5'-phosphate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP).

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Pyridoxal Phosphate-d<sub>3</sub>

Pyridoxal Phosphate-d3 Estructura química

No. CAS : 1354560-58-9

Tamaño Precio Stock Cantidad
500 μg En stock
1 mg En stock
5 mg   Obtener un presupuesto  
10 mg   Obtener un presupuesto  

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Other Forms of Pyridoxal Phosphate-d3:

Pyridoxal Phosphate-d3 Related Antibodies

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Descripciòn

Pyridoxal Phosphate-d3 is the deuterium labeled Pyridoxal 5'-phosphate. Pyridoxal 5'-phosphate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP)[1][2].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Pyridoxal Phosphate-d3 Related Antibodies
Peso molecular

250.16

Fòrmula

C8H7D3NO6P
No. CAS
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

O=CC1=C(O)C(C([2H])([2H])[2H])=NC=C1COP(O)(O)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 62.5 mg/mL (249.84 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9974 mL 19.9872 mL 39.9744 mL
5 mM 0.7995 mL 3.9974 mL 7.9949 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 98.01%

SDS (252 KB)

COA (251 KB) HNMR (109 KB) RP-HPLC (198 KB) LCMS (88 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9974 mL 19.9872 mL 39.9744 mL 99.9360 mL
5 mM 0.7995 mL 3.9974 mL 7.9949 mL 19.9872 mL
10 mM 0.3997 mL 1.9987 mL 3.9974 mL 9.9936 mL
15 mM 0.2665 mL 1.3325 mL 2.6650 mL 6.6624 mL
20 mM 0.1999 mL 0.9994 mL 1.9987 mL 4.9968 mL
25 mM 0.1599 mL 0.7995 mL 1.5990 mL 3.9974 mL
30 mM 0.1332 mL 0.6662 mL 1.3325 mL 3.3312 mL
40 mM 0.0999 mL 0.4997 mL 0.9994 mL 2.4984 mL
50 mM 0.0799 mL 0.3997 mL 0.7995 mL 1.9987 mL
60 mM 0.0666 mL 0.3331 mL 0.6662 mL 1.6656 mL
80 mM 0.0500 mL 0.2498 mL 0.4997 mL 1.2492 mL
100 mM 0.0400 mL 0.1999 mL 0.3997 mL 0.9994 mL
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Pyridoxal Phosphate-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pyridoxal Phosphate-d31354560-58-9Pyridoxal 5'-phosphate-d3Endogenous MetaboliteAmyloid-βERKβ-amyloid peptideAβAbetaExtracellular signal regulated kinasesInhibitorinhibitorinhibit

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Nombre del producto:
Pyridoxal Phosphate-d3
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HY-W011727S
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