1. Metabolic Enzyme/Protease MAPK/ERK Pathway Protein Tyrosine Kinase/RTK
  2. Drug Metabolite Raf VEGFR c-Kit
  3. Regorafenib N-oxide and N-desmethyl (M5)

Regorafenib N-oxide and N-desmethyl (M5)  (Synonyms: N-Desmethyl regorafenib N-oxide)

Cat. No.: HY-108226
Instrucciones de manejo Technical Support

Regorafenib N-oxide and N-desmethyl (M5) (N-Desmethyl regorafenib N-oxide) is an active metabolite of Sorafenib (HY-10201) and can be metabolized by CYP3A4.

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Regorafenib N-oxide and N-desmethyl (M5)

Regorafenib N-oxide and N-desmethyl (M5) Estructura química

No. CAS : 835621-12-0

Tamaño Precio Stock Cantidad
25 mg Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 mg Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 mg Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 mg Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
1 g Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
5 g   Obtener un presupuesto  
10 g   Obtener un presupuesto  
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Descripciòn

Regorafenib N-oxide and N-desmethyl (M5) (N-Desmethyl regorafenib N-oxide) is an active metabolite of Sorafenib (HY-10201) and can be metabolized by CYP3A4[1].

Peso molecular

484.79

Fòrmula

C20H13ClF4N4O4

No. CAS
SMILES

O=C(C1=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C(F)=C2)=CC=[N+]1[O-])N

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
Regorafenib N-oxide and N-desmethyl (M5)
Cat. No.:
HY-108226
Cantidad:
MCE Japan Authorized Agent: