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  2. Isotope-Labeled Compounds
  3. Regorafenib N-oxide and N-desmethyl (M5)-13C6

Regorafenib N-oxide and N-desmethyl (M5)-13C6 is the 13C-labeled Regorafenib N-oxide and N-desmethyl (M5).

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Regorafenib N-oxide and N-desmethyl (M5)-<sup>13</sup>C<sub>6</sub>

Regorafenib N-oxide and N-desmethyl (M5)-13C6 Chemische Struktur

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Beschreibung

Regorafenib N-oxide and N-desmethyl (M5)-13C6 is the 13C-labeled Regorafenib N-oxide and N-desmethyl (M5)[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

490.74

Formel

C1413C6H13ClF4N4O4

Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC(OC2=CC=C(C(F)=C2)NC(N[13C]3=[13CH][13CH]=[13C]([13C](C(F)(F)F)=[13CH]3)Cl)=O)=CC=[N+]1[O-])N

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reinheit & Dokumentation

Purity: ≥91.0%

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  • Molaritätsrechner

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Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Produktname:
Regorafenib N-oxide and N-desmethyl (M5)-13C6
Art. -Nr.:
HY-108226S1
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