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  2. Isotope-Labeled Compounds
  3. Regorafenib N-oxide and N-desmethyl (M5)-13C6

Regorafenib N-oxide and N-desmethyl (M5)-13C6 

Cat. No.: HY-108226S1
COA Handling Instructions

Regorafenib N-oxide and N-desmethyl (M5)-13C6 is the 13C-labeled Regorafenib N-oxide and N-desmethyl (M5)[1].

For research use only. We do not sell to patients.

Regorafenib N-oxide and N-desmethyl (M5)-<sup>13</sup>C<sub>6</sub> Chemical Structure

Regorafenib N-oxide and N-desmethyl (M5)-13C6 Chemical Structure

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Description

Regorafenib N-oxide and N-desmethyl (M5)-13C6 is the 13C-labeled Regorafenib N-oxide and N-desmethyl (M5)[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

490.74

Formula

C1413C6H13ClF4N4O4

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC(OC2=CC=C(C(F)=C2)NC(N[13C]3=[13CH][13CH]=[13C]([13C](C(F)(F)F)=[13CH]3)Cl)=O)=CC=[N+]1[O-])N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥91.0%

References
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Regorafenib N-oxide and N-desmethyl (M5)-13C6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Regorafenib N-oxide and N-desmethyl (M5)-13C6
Cat. No.:
HY-108226S1
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